Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1570280..1571193 Replicon chromosome
Accession NZ_CP043438
Organism Enterobacter sp. LU1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FZF21_RS07515 Protein ID WP_032647883.1
Coordinates 1570280..1570753 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FZF21_RS07520 Protein ID WP_023296216.1
Coordinates 1570750..1571193 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZF21_RS07490 1566194..1566637 + 444 WP_047737756.1 hypothetical protein -
FZF21_RS07495 1568009..1568467 + 459 Protein_1449 type I-F CRISPR-associated endonuclease Cas1 -
FZF21_RS07500 1568436..1568681 + 246 Protein_1450 type I-F CRISPR-associated protein Csy2 -
FZF21_RS07505 1568695..1569693 + 999 WP_149120988.1 type I-F CRISPR-associated protein Csy3 -
FZF21_RS07510 1569703..1570257 + 555 WP_023296214.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
FZF21_RS07515 1570280..1570753 - 474 WP_032647883.1 RES domain-containing protein Toxin
FZF21_RS07520 1570750..1571193 - 444 WP_023296216.1 DUF2384 domain-containing protein Antitoxin
FZF21_RS07525 1572413..1572631 - 219 WP_002211347.1 translation initiation factor IF-1 -
FZF21_RS07530 1572916..1573620 - 705 WP_047737743.1 leucyl/phenylalanyl-tRNA--protein transferase -
FZF21_RS07535 1573666..1575387 - 1722 WP_047737741.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17569.96 Da        Isoelectric Point: 5.5555

>T138771 WP_032647883.1 NZ_CP043438:c1570753-1570280 [Enterobacter sp. LU1]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Download         Length: 474 bp

>T138771 NZ_CP058222:4698499-4698876 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACCCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGAATTC
AGTGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCACGCCGGGCAACCGGCCTGATGACCCGCGA
CAACTACAGAACGGTAAATGACATTACCCTGGGTAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16512.81 Da        Isoelectric Point: 6.4819

>AT138771 WP_023296216.1 NZ_CP043438:c1571193-1570750 [Enterobacter sp. LU1]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT138771 NZ_CP058222:4698041-4698409 [Escherichia coli]
GTGTCAGACACACTGCCCGGGACAACGCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCATACCATCTGGGCCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGATACCCTCGGCAGCTG
TGGTTGCGTTTATCTGGCTGTTTATCCGACACCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References