Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 339430..339701 Replicon chromosome
Accession NZ_CP043406
Organism Escherichia coli strain NMBU-W13E19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 339560..339663 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 339430..339701 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZN32_RS01675 335985..336647 - 663 WP_000944256.1 exodeoxyribonuclease X -
FZN32_RS01680 336671..337327 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
FZN32_RS01685 337429..337659 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FZN32_RS01690 337798..338172 + 375 WP_000204705.1 CopC domain-containing protein YobA -
FZN32_RS01695 338176..339048 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
FZN32_RS01700 339061..339402 + 342 WP_000976481.1 YebY family protein -
- 339430..339701 - 272 - - Antitoxin
- 339560..339663 + 104 - - Toxin
FZN32_RS01705 339798..340454 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
FZN32_RS01710 340455..340646 - 192 WP_001296140.1 YebW family protein -
FZN32_RS01715 340751..340987 - 237 WP_001295499.1 DUF1480 family protein -
FZN32_RS01720 341105..342544 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 332120..356251 24131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T138671 NZ_CP043406:339560-339663 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT138671 NZ_CP043406:c339701-339430 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References