Detailed information of TA system TA138660

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 932756..934440
• Replicon: chromosome
• Accession: NZ_CP043403
• Organism: Xanthomonas oryzae pv. oryzicola strain GX01

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: XOCgx_RS04495
• Protein ID: WP_149621356.1
• Coordinates: 933826..934440 (-)
• Length: 205 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: XOCgx_RS04490
• Protein ID: WP_149621355.1
• Coordinates: 932756..933829 (-)
• Length: 358 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XOCgx_RS04470	928631..928957	-	327	WP_024710580.1	hypothetical protein	-
XOCgx_RS04475	929261..930541	-	1281	WP_024710581.1	amidohydrolase family protein	-
XOCgx_RS04480	930538..931947	-	1410	WP_024710582.1	amidohydrolase	-
XOCgx_RS04485	932087..932647	+	561	WP_044750878.1	DUF924 family protein	-
XOCgx_RS04490	932756..933829	-	1074	WP_149621355.1	macro domain-containing protein	Antitoxin
XOCgx_RS04495	933826..934440	-	615	WP_149621356.1	DUF4433 domain-containing protein	Toxin
XOCgx_RS04500	934810..935736	-	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
XOCgx_RS04505	935782..936573	+	792	WP_024710587.1	polysaccharide deacetylase family protein	-
XOCgx_RS04515	936877..937548	-	672	WP_024745633.1	class I SAM-dependent methyltransferase	-
XOCgx_RS04520	937871..938521	-	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-203)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 205 a.a.
• Molecular weight: 23757.97 Da
• Isoelectric Point: 7.9242

>T138660 WP_149621356.1 NZ_CP043403:c934440-933826 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSIGNPELIDKRSSHPVPRPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHVPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 615 bp

>T138660 NZ_CP058192:c140366-139881 [Enterobacter hormaechei]
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA

Antitoxin

Protein

• Length: 358 a.a.
• Molecular weight: 40084.13 Da
• Isoelectric Point: 6.0089

>AT138660 WP_149621355.1 NZ_CP043403:c933829-932756 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGI
RHWPGDQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1074 bp

>AT138660 NZ_CP058192:c140620-140354 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA