Detailed information of TA system TA138659

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 645261..646840
• Replicon: chromosome
• Accession: NZ_CP043403
• Organism: Xanthomonas oryzae pv. oryzicola strain GX01

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: XOCgx_RS03085
• Protein ID: WP_149621311.1
• Coordinates: 645261..646526 (+)
• Length: 422 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: A0A0C5UZA4
• Locus tag: XOCgx_RS03090
• Protein ID: WP_044749828.1
• Coordinates: 646544..646840 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XOCgx_RS03065	641254..641532	-	279	WP_047340320.1	type I toxin-antitoxin system SymE family toxin	-
XOCgx_RS03075	642269..644347	+	2079	Protein_546	hemagglutinin repeat-containing protein	-
XOCgx_RS03080	644401..644886	+	486	Protein_547	IS30-like element IS1112a family transposase	-
XOCgx_RS03085	645261..646526	+	1266	WP_149621311.1	avirulence protein	Toxin
XOCgx_RS03090	646544..646840	+	297	WP_044749828.1	hypothetical protein	Antitoxin
XOCgx_RS03095	647062..647328	+	267	Protein_550	transposase	-
XOCgx_RS03100	647395..647820	-	426	Protein_551	DDE-type integrase/transposase/recombinase	-
XOCgx_RS03105	647889..648990	+	1102	WP_149621312.1	IS3 family transposase	-
XOCgx_RS03110	649020..649097	+	78	Protein_553	anti-sigma factor antagonist	-
XOCgx_RS03115	649192..649367	+	176	Protein_554	HAD family hydrolase	-
XOCgx_RS03120	649583..650335	-	753	WP_024712407.1	YceI family protein	-
XOCgx_RS03125	650546..651136	-	591	WP_014504809.1	malonic semialdehyde reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	640811..656771	15960
	-	inside	IScluster/Tn	-	-	633634..648990	15356

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (149-291)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 422 a.a.
• Molecular weight: 45201.81 Da
• Isoelectric Point: 6.9140

>T138659 WP_149621311.1 NZ_CP043403:645261-646526 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVATVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI

Nucleotide

• Length: 1266 bp

>T138659 NZ_CP058192:81526-81813 [Enterobacter hormaechei]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11327.83 Da
• Isoelectric Point: 5.2138

>AT138659 WP_044749828.1 NZ_CP043403:646544-646840 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS

Nucleotide

• Length: 297 bp

>AT138659 NZ_CP043403:646544-646840 [Xanthomonas oryzae pv. oryzicola]
ATGAAAACTTTGACAGGCGCAGACGCACTCGAATTTCATAAGAAGCTTAAGGAACGTAATAAAGCCTTACATGCTTCCGA
CCTCGAGTTAGCACTGGTGCACGCCGATGCTGTCGGCAAAGAACGGTTCGATCTCGAGGAGCTGGAGAAAATTTGCGATA
CCAGCGATGCGGGGCGCCTTACTGATGCGAAAGAGCGACACGACATATATGAACGGATGTACTACGTTGAGTATCCCAAC
GTTATGACGTTAAAGGAATTCGCTCATATCGTCGAGACACTTTCCTCGTGGTCATGA

Structures

Antitoxin

• AlphaFold DB: A0A0C5UZA4