Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4892736..4893322 Replicon chromosome
Accession NZ_CP043396
Organism Pseudomonas monteilii strain 170620603RE

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FY043_RS23285 Protein ID WP_082426425.1
Coordinates 4893029..4893322 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A923H277
Locus tag FY043_RS23280 Protein ID WP_060499950.1
Coordinates 4892736..4893032 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY043_RS23260 4889704..4890645 - 942 WP_164525071.1 FecR domain-containing protein -
FY043_RS23265 4890645..4891157 - 513 WP_164525274.1 sigma-70 family RNA polymerase sigma factor -
FY043_RS23270 4891447..4892094 + 648 WP_060499948.1 hypothetical protein -
FY043_RS23275 4892246..4892734 + 489 WP_164525072.1 GNAT family N-acetyltransferase -
FY043_RS23280 4892736..4893032 - 297 WP_060499950.1 putative addiction module antidote protein Antitoxin
FY043_RS23285 4893029..4893322 - 294 WP_082426425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY043_RS23290 4893544..4894431 + 888 WP_164525073.1 effector protein -
FY043_RS23295 4894428..4895195 - 768 WP_060499952.1 phosphonate ABC transporter, permease protein PhnE -
FY043_RS23300 4895192..4896019 - 828 WP_060499953.1 ABC transporter permease subunit -
FY043_RS23305 4896013..4896822 - 810 WP_164525074.1 ATP-binding cassette domain-containing protein -
FY043_RS23310 4896819..4897673 - 855 WP_164525075.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4846218..4894431 48213


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10847.80 Da        Isoelectric Point: 10.5184

>T138629 WP_082426425.1 NZ_CP043396:c4893322-4893029 [Pseudomonas monteilii]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI

Download         Length: 294 bp

>T138629 NZ_CP058177:46844-47185 [Enterobacter hormaechei]
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGCGACGCTATGTCTGTCGCCTGTGGCAGTCTGGCAAATGCTGCTTGC
TCGCCTGCTGGAACAACATTATGGCCTGACGCTAAACGACACGCCGTTCAGTGATGAAAAGGTAATTCAGGAACATATCG
ATGCCGGTATATCTTTGGCCGATGCCGTTAATTTTCTGGTGGAAAAGTACGGGCTGGTTCGTATTGATCGCAGGGGATTC
GGCTGGCAAGAACAGTCCCCATATCTGCGGGCAGTCGATATTCTGCGGGCGCGACAGGCAACAGGTTTATTGAAAGCGCG
GCACGGTGAACATTGGGAATAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10587.22 Da        Isoelectric Point: 6.2205

>AT138629 WP_060499950.1 NZ_CP043396:c4893032-4892736 [Pseudomonas monteilii]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR

Download         Length: 297 bp

>AT138629 NZ_CP058177:46482-46823 [Enterobacter hormaechei]
ATGAAATCTACTGATTCAGAGAACGATTCATTTCTCAAGTGGGGTCTGAATCGTAATGTGACACCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAATCGACTGCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTCAGCGAAGCAGAATGTC
TTAAGCTGGATTTGGCATTCCCGCATTTTATCAGCCAGATGGAATCGATGCTGACTACTGGTGAAATAAATCCTCGCCAT
GCCCACTGTGTCACCCTGTACCACAATGGTTTCACCTGCGAAGCCGATTCCCTTGGCAGTTGCGGCTACGTATACATCGC
CGTTTACCTCACTTATCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References