Detailed information of TA system TA138625

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PfiT-PfiA/ParE(toxin)
• Location: 345707..346313
• Replicon: chromosome
• Accession: NZ_CP043396
• Organism: Pseudomonas monteilii strain 170620603RE

Toxin (Protein)

• Gene name: PfiT
• Uniprot ID: A0A6G6UCX8
• Locus tag: FY043_RS01535
• Protein ID: WP_060501213.1
• Coordinates: 345707..346054 (-)
• Length: 116 a.a.

Antitoxin (Protein)

• Gene name: PfiA
• Uniprot ID: A0A923H1P8
• Locus tag: FY043_RS01540
• Protein ID: WP_025754068.1
• Coordinates: 346065..346313 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FY043_RS01520	341140..342507	-	1368	WP_164524045.1	HAMP domain-containing protein	-
FY043_RS01525	342509..343231	-	723	WP_060501217.1	response regulator	-
FY043_RS01530	343372..345669	+	2298	WP_164524046.1	TonB-dependent siderophore receptor	-
FY043_RS01535	345707..346054	-	348	WP_060501213.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FY043_RS01540	346065..346313	-	249	WP_025754068.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FY043_RS01545	347214..348113	-	900	WP_164524047.1	hypothetical protein	-
FY043_RS01550	348116..349231	-	1116	WP_164524048.1	DUF3696 domain-containing protein	-
FY043_RS01555	349228..350481	-	1254	WP_206520113.1	DUF262 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-100)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 116 a.a.
• Molecular weight: 12751.62 Da
• Isoelectric Point: 6.6372

>T138625 WP_060501213.1 NZ_CP043396:c346054-345707 [Pseudomonas monteilii]
MSKPTIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNVDGYRVFY
EVIETDNAIAVGLVLRQKQSVEQALIRYCLIYPLP

Nucleotide

• Length: 348 bp

>T138625 NZ_CP058175:c2411923-2411438 [Enterobacter hormaechei]
GTGGGACGTGTAACCGCCCCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGTGGAGAGGCCGTACTTGA
CGAATGGTTAAAACAAAGAGGTCTGAAAAACCAGGCGCTTGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACAA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGGAAGCGACAGGTAATTTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATTCTTGCCCGTCTGGCTGTCGATGTCTCAATACGCGGAAATGGGTTGGGAGCCGATTT
ACTCCAGGATGCGGTTTTACGCTGTTATCGGGTAGCAGAGAATATTGGGGTGCGGGCGATCATGGTTCATGCACTCACTG
AAAAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9307.61 Da
• Isoelectric Point: 6.4706

>AT138625 WP_025754068.1 NZ_CP043396:c346313-346065 [Pseudomonas monteilii]
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKTRLLKKFS
EE

Nucleotide

• Length: 249 bp

>AT138625 NZ_CP058175:c2412177-2411911 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAATCTTAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTACA
TAAATCACGTACTGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAAAATGTGATCCTCGATCGGCGTGTATTCAATT
TTAACGATGAACAGTATGCAGAGTTCATTGATATGCTTGATGCCCCGGTCGCCGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Structures

Toxin

• AlphaFold DB: A0A6G6UCX8