Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4893845..4894431 Replicon chromosome
Accession NZ_CP043395
Organism Pseudomonas monteilii strain 170918607

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FY041_RS23300 Protein ID WP_082426425.1
Coordinates 4894138..4894431 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A923H277
Locus tag FY041_RS23295 Protein ID WP_060499950.1
Coordinates 4893845..4894141 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY041_RS23275 4890813..4891754 - 942 WP_164525071.1 FecR domain-containing protein -
FY041_RS23280 4891754..4892266 - 513 WP_164525274.1 sigma-70 family RNA polymerase sigma factor -
FY041_RS23285 4892556..4893203 + 648 WP_060499948.1 hypothetical protein -
FY041_RS23290 4893355..4893843 + 489 WP_164525072.1 GNAT family N-acetyltransferase -
FY041_RS23295 4893845..4894141 - 297 WP_060499950.1 putative addiction module antidote protein Antitoxin
FY041_RS23300 4894138..4894431 - 294 WP_082426425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY041_RS23305 4894653..4895540 + 888 WP_164525073.1 effector protein -
FY041_RS23310 4895537..4896304 - 768 WP_060499952.1 phosphonate ABC transporter, permease protein PhnE -
FY041_RS23315 4896301..4897128 - 828 WP_060499953.1 ABC transporter permease subunit -
FY041_RS23320 4897122..4897931 - 810 WP_164525074.1 ATP-binding cassette domain-containing protein -
FY041_RS23325 4897928..4898782 - 855 WP_164525075.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10847.80 Da        Isoelectric Point: 10.5184

>T138624 WP_082426425.1 NZ_CP043395:c4894431-4894138 [Pseudomonas monteilii]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI

Download         Length: 294 bp

>T138624 NZ_CP058175:c1176795-1176577 [Enterobacter hormaechei]
ATGTCTGATAAACCATTAACTAAAGTCGATTATTTGATGCGCCTGCGACGCTGTCAGTCAATTGACACGCTCGAACGTGT
TATTGAGAAAAATAAATACGAGCTGTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTTGCTGAAC
TGACCATGAATAAACTCTATGACAAGATCCCCTCTTCGGTATGGAAATTTGTTCGTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10587.22 Da        Isoelectric Point: 6.2205

>AT138624 WP_060499950.1 NZ_CP043395:c4894141-4893845 [Pseudomonas monteilii]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR

Download         Length: 297 bp

>AT138624 NZ_CP058175:c1177198-1176824 [Enterobacter hormaechei]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTTAATGAGCTGATCGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGTCT
ATTTCGCTGCTTCACGAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References