Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 4893845..4894431 | Replicon | chromosome |
Accession | NZ_CP043395 | ||
Organism | Pseudomonas monteilii strain 170918607 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | FY041_RS23300 | Protein ID | WP_082426425.1 |
Coordinates | 4894138..4894431 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A923H277 |
Locus tag | FY041_RS23295 | Protein ID | WP_060499950.1 |
Coordinates | 4893845..4894141 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FY041_RS23275 | 4890813..4891754 | - | 942 | WP_164525071.1 | FecR domain-containing protein | - |
FY041_RS23280 | 4891754..4892266 | - | 513 | WP_164525274.1 | sigma-70 family RNA polymerase sigma factor | - |
FY041_RS23285 | 4892556..4893203 | + | 648 | WP_060499948.1 | hypothetical protein | - |
FY041_RS23290 | 4893355..4893843 | + | 489 | WP_164525072.1 | GNAT family N-acetyltransferase | - |
FY041_RS23295 | 4893845..4894141 | - | 297 | WP_060499950.1 | putative addiction module antidote protein | Antitoxin |
FY041_RS23300 | 4894138..4894431 | - | 294 | WP_082426425.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FY041_RS23305 | 4894653..4895540 | + | 888 | WP_164525073.1 | effector protein | - |
FY041_RS23310 | 4895537..4896304 | - | 768 | WP_060499952.1 | phosphonate ABC transporter, permease protein PhnE | - |
FY041_RS23315 | 4896301..4897128 | - | 828 | WP_060499953.1 | ABC transporter permease subunit | - |
FY041_RS23320 | 4897122..4897931 | - | 810 | WP_164525074.1 | ATP-binding cassette domain-containing protein | - |
FY041_RS23325 | 4897928..4898782 | - | 855 | WP_164525075.1 | putative selenate ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10847.80 Da Isoelectric Point: 10.5184
>T138624 WP_082426425.1 NZ_CP043395:c4894431-4894138 [Pseudomonas monteilii]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI
Download Length: 294 bp
>T138624 NZ_CP058175:c1176795-1176577 [Enterobacter hormaechei]
ATGTCTGATAAACCATTAACTAAAGTCGATTATTTGATGCGCCTGCGACGCTGTCAGTCAATTGACACGCTCGAACGTGT
TATTGAGAAAAATAAATACGAGCTGTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTTGCTGAAC
TGACCATGAATAAACTCTATGACAAGATCCCCTCTTCGGTATGGAAATTTGTTCGTTAG
ATGTCTGATAAACCATTAACTAAAGTCGATTATTTGATGCGCCTGCGACGCTGTCAGTCAATTGACACGCTCGAACGTGT
TATTGAGAAAAATAAATACGAGCTGTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTTGCTGAAC
TGACCATGAATAAACTCTATGACAAGATCCCCTCTTCGGTATGGAAATTTGTTCGTTAG
Antitoxin
Download Length: 99 a.a. Molecular weight: 10587.22 Da Isoelectric Point: 6.2205
>AT138624 WP_060499950.1 NZ_CP043395:c4894141-4893845 [Pseudomonas monteilii]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR
Download Length: 297 bp
>AT138624 NZ_CP058175:c1177198-1176824 [Enterobacter hormaechei]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTTAATGAGCTGATCGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGTCT
ATTTCGCTGCTTCACGAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTTAATGAGCTGATCGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGTCT
ATTTCGCTGCTTCACGAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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