Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2033440..2033585 Replicon chromosome
Accession NZ_CP043378
Organism Klebsiella pneumoniae strain WCHKP095005

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2033476..2033578 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2033440..2033585 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D44_RS09835 2028570..2030630 + 2061 WP_004151449.1 oligopeptidase B -
B7D44_RS09840 2030634..2031293 - 660 WP_002911407.1 exodeoxyribonuclease X -
B7D44_RS09845 2031372..2031602 - 231 WP_002911406.1 DNA polymerase III subunit theta -
B7D44_RS09850 2031715..2032089 + 375 WP_039819395.1 CopC domain-containing protein YobA -
B7D44_RS09855 2032093..2032962 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
B7D44_RS09860 2032979..2033317 + 339 WP_002911404.1 YebY family protein -
- 2033440..2033585 - 146 - - Antitoxin
- 2033476..2033578 + 103 - - Toxin
B7D44_RS09865 2033954..2034097 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
B7D44_RS09870 2034202..2035170 - 969 WP_014907334.1 VirK/YbjX family protein -
B7D44_RS09875 2035327..2035980 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
B7D44_RS09880 2035977..2036168 - 192 WP_002911395.1 YebW family protein -
B7D44_RS09885 2036266..2036505 - 240 WP_002911393.1 YebV family protein -
B7D44_RS09890 2036621..2038054 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138542 NZ_CP043378:2033476-2033578 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138542 NZ_CP043378:c2033585-2033440 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References