Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1837771..1837916 Replicon chromosome
Accession NZ_CP043362
Organism Klebsiella pneumoniae strain WCHKP085104

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1837807..1837909 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1837771..1837916 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D52_RS08900 1832901..1834961 + 2061 WP_004151449.1 oligopeptidase B -
B7D52_RS08905 1834965..1835624 - 660 WP_002911407.1 exodeoxyribonuclease X -
B7D52_RS08910 1835703..1835933 - 231 WP_048254886.1 DNA polymerase III subunit theta -
B7D52_RS08915 1836046..1836420 + 375 WP_004151448.1 CopC domain-containing protein YobA -
B7D52_RS08920 1836424..1837293 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
B7D52_RS08925 1837310..1837648 + 339 WP_016529031.1 YebY family protein -
- 1837771..1837916 - 146 - - Antitoxin
- 1837807..1837909 + 103 - - Toxin
B7D52_RS08930 1838284..1838427 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
B7D52_RS08935 1838532..1839500 - 969 WP_004151446.1 VirK/YbjX family protein -
B7D52_RS08940 1839657..1840310 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
B7D52_RS08945 1840307..1840498 - 192 WP_002911395.1 YebW family protein -
B7D52_RS08950 1840596..1840835 - 240 WP_002911393.1 YebV family protein -
B7D52_RS08955 1840951..1842384 - 1434 WP_071081310.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138520 NZ_CP043362:1837807-1837909 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138520 NZ_CP043362:c1837916-1837771 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References