Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021623..2021768 Replicon chromosome
Accession NZ_CP043357
Organism Klebsiella pneumoniae subsp. pneumoniae strain WCHKP020120

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2021659..2021761 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021623..2021768 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ78_RS09875 (CLQ78_09875) 2016753..2018813 + 2061 WP_004151449.1 oligopeptidase B -
CLQ78_RS09880 (CLQ78_09880) 2018817..2019476 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLQ78_RS09885 (CLQ78_09885) 2019555..2019785 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ78_RS09890 (CLQ78_09890) 2019898..2020272 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ78_RS09895 (CLQ78_09895) 2020276..2021145 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CLQ78_RS09900 (CLQ78_09900) 2021162..2021500 + 339 WP_002911404.1 YebY family protein -
- 2021623..2021768 - 146 - - Antitoxin
- 2021659..2021761 + 103 - - Toxin
CLQ78_RS09905 (CLQ78_09905) 2022136..2022279 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ78_RS09910 (CLQ78_09910) 2022384..2023352 - 969 WP_004151446.1 VirK/YbjX family protein -
CLQ78_RS09915 (CLQ78_09915) 2023509..2024162 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CLQ78_RS09920 (CLQ78_09920) 2024159..2024350 - 192 WP_002911395.1 YebW family protein -
CLQ78_RS09925 (CLQ78_09925) 2024448..2024687 - 240 WP_002911393.1 YebV family protein -
CLQ78_RS09930 (CLQ78_09930) 2024803..2026236 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138492 NZ_CP043357:2021659-2021761 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138492 NZ_CP043357:c2021768-2021623 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References