Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2040335..2040480 Replicon chromosome
Accession NZ_CP043353
Organism Klebsiella pneumoniae strain WCHKP020115

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2040371..2040473 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2040335..2040480 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6M09_RS09975 (C6M09_09975) 2035465..2037525 + 2061 WP_004151449.1 oligopeptidase B -
C6M09_RS09980 (C6M09_09980) 2037529..2038188 - 660 WP_002911407.1 exodeoxyribonuclease X -
C6M09_RS09985 (C6M09_09985) 2038267..2038497 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C6M09_RS09990 (C6M09_09990) 2038610..2038984 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C6M09_RS09995 (C6M09_09995) 2038988..2039857 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C6M09_RS10000 (C6M09_10000) 2039874..2040212 + 339 WP_002911404.1 YebY family protein -
- 2040335..2040480 - 146 - - Antitoxin
- 2040371..2040473 + 103 - - Toxin
C6M09_RS10005 (C6M09_10005) 2040848..2040991 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C6M09_RS10010 (C6M09_10010) 2041096..2042064 - 969 WP_004151446.1 VirK/YbjX family protein -
C6M09_RS10015 (C6M09_10015) 2042221..2042874 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C6M09_RS10020 (C6M09_10020) 2042871..2043062 - 192 WP_002911395.1 YebW family protein -
C6M09_RS10025 (C6M09_10025) 2043160..2043399 - 240 WP_002911393.1 YebV family protein -
C6M09_RS10030 (C6M09_10030) 2043515..2044948 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138468 NZ_CP043353:2040371-2040473 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138468 NZ_CP043353:c2040480-2040335 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References