Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1901665..1901810 Replicon chromosome
Accession NZ_CP043348
Organism Klebsiella pneumoniae strain WCHKP020097

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1901701..1901803 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1901665..1901810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAY71_RS09125 1896795..1898855 + 2061 WP_032419805.1 oligopeptidase B -
CAY71_RS09130 1898859..1899518 - 660 WP_002911407.1 exodeoxyribonuclease X -
CAY71_RS09135 1899597..1899827 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CAY71_RS09140 1899940..1900314 + 375 WP_020316569.1 CopC domain-containing protein YobA -
CAY71_RS09145 1900318..1901187 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CAY71_RS09150 1901204..1901542 + 339 WP_002911404.1 YebY family protein -
- 1901665..1901810 - 146 - - Antitoxin
- 1901701..1901803 + 103 - - Toxin
CAY71_RS09155 1902178..1902321 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CAY71_RS09160 1902426..1903394 - 969 WP_014907334.1 VirK/YbjX family protein -
CAY71_RS09165 1903551..1904204 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
CAY71_RS09170 1904201..1904392 - 192 WP_002911395.1 YebW family protein -
CAY71_RS09175 1904490..1904729 - 240 WP_002911393.1 YebV family protein -
CAY71_RS09180 1904845..1906278 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138447 NZ_CP043348:1901701-1901803 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138447 NZ_CP043348:c1901810-1901665 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References