138425

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018128..2018273 Replicon chromosome
Accession NZ_CP043344
Organism Klebsiella pneumoniae subsp. pneumoniae strain WCHKP020039

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018164..2018266 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018128..2018273 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVC44_RS09880 (CVC44_10030) 2013258..2015318 + 2061 WP_004151449.1 oligopeptidase B -
CVC44_RS09885 (CVC44_10035) 2015322..2015981 - 660 WP_002911407.1 exodeoxyribonuclease X -
CVC44_RS09890 (CVC44_10040) 2016060..2016290 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CVC44_RS09895 (CVC44_10045) 2016403..2016777 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CVC44_RS09900 (CVC44_10050) 2016781..2017650 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CVC44_RS09905 (CVC44_10055) 2017667..2018005 + 339 WP_002911404.1 YebY family protein -
- 2018128..2018273 - 146 - - Antitoxin
- 2018164..2018266 + 103 - - Toxin
CVC44_RS09910 (CVC44_10065) 2018641..2018784 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CVC44_RS09915 (CVC44_10070) 2018889..2019857 - 969 WP_004151446.1 VirK/YbjX family protein -
CVC44_RS09920 (CVC44_10075) 2020014..2020667 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CVC44_RS09925 (CVC44_10080) 2020664..2020855 - 192 WP_002911395.1 YebW family protein -
CVC44_RS09930 (CVC44_10085) 2020953..2021192 - 240 WP_002911393.1 YebV family protein -
CVC44_RS09935 (CVC44_10090) 2021308..2022741 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T138425 NZ_CP043344:2018164-2018266 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT138425 NZ_CP043344:c2018273-2018128 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References