Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3133928..3134475 Replicon chromosome
Accession NZ_CP043320
Organism Pseudomonas sp. C27(2019)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FXF61_RS14455 Protein ID WP_151185909.1
Coordinates 3134173..3134475 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXF61_RS14450 Protein ID WP_151185908.1
Coordinates 3133928..3134185 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXF61_RS14400 3129098..3130219 + 1122 WP_151185899.1 Fic family protein -
FXF61_RS14405 3130311..3130775 + 465 WP_151185900.1 bacterioferritin -
FXF61_RS14410 3130871..3131007 - 137 Protein_2819 phage integrase N-terminal SAM-like domain-containing protein -
FXF61_RS14415 3131386..3131655 + 270 WP_151185901.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
FXF61_RS14420 3131656..3131949 + 294 WP_151185902.1 type II toxin-antitoxin system RelE/ParE family toxin -
FXF61_RS14425 3132071..3132385 + 315 WP_151185903.1 transcriptional regulator -
FXF61_RS14430 3132378..3132677 + 300 WP_151185904.1 helix-turn-helix domain-containing protein -
FXF61_RS14435 3132757..3133257 + 501 WP_151185905.1 GNAT family N-acetyltransferase -
FXF61_RS14440 3133329..3133592 + 264 WP_151185906.1 BrnT family toxin -
FXF61_RS14445 3133582..3133851 + 270 WP_151185907.1 CopG family transcriptional regulator -
FXF61_RS14450 3133928..3134185 + 258 WP_151185908.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXF61_RS14455 3134173..3134475 + 303 WP_151185909.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXF61_RS14460 3134572..3135369 + 798 WP_151185910.1 PhzF family phenazine biosynthesis protein -
FXF61_RS14465 3135870..3137372 + 1503 WP_151185911.1 DUF3375 domain-containing protein -
FXF61_RS14470 3137375..3138079 + 705 WP_151185912.1 DUF4194 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11722.43 Da        Isoelectric Point: 4.4003

>T138358 WP_151185909.1 NZ_CP043320:3134173-3134475 [Pseudomonas sp. C27(2019)]
MAEIIWTEPALQELDALAEYVALDNPEAASHLVEKVFDKVERLENFPQSGRVPPELPNSVYREVVVPPCRIFYREDDKRV
LILYVMREERQLRAYMLESS

Download         Length: 303 bp

>T138358 NZ_CP043320:3134173-3134475 [Pseudomonas sp. C27(2019)]
ATGGCTGAAATAATCTGGACGGAGCCAGCCCTTCAGGAACTGGATGCTCTCGCGGAGTATGTTGCGTTGGATAATCCTGA
AGCGGCCAGCCATTTGGTCGAAAAAGTGTTTGATAAAGTTGAGCGTCTGGAGAATTTTCCCCAATCTGGACGGGTTCCTC
CAGAACTGCCCAATTCCGTATACAGGGAAGTAGTAGTGCCTCCGTGTCGCATTTTTTATCGAGAAGATGATAAGCGGGTT
CTTATCCTATATGTCATGCGAGAGGAGCGGCAGCTTCGCGCTTACATGCTGGAGAGCAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9905.48 Da        Isoelectric Point: 9.9123

>AT138358 WP_151185908.1 NZ_CP043320:3133928-3134185 [Pseudomonas sp. C27(2019)]
MKVELVTNLKRQATKILADLRLSKEPVLITEHGQPSAYLVNVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp

>AT138358 NZ_CP057632:775509-775952 [Citrobacter sp. RHB20-C15]
ATGAAAACTTTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAACCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCAACCACATTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGTATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAGGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAAACGGGAGCCTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References