Detailed information of TA system TA138357

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 3133329..3133851
• Replicon: chromosome
• Accession: NZ_CP043320
• Organism: Pseudomonas sp. C27(2019)

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FXF61_RS14440
• Protein ID: WP_151185906.1
• Coordinates: 3133329..3133592 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FXF61_RS14445
• Protein ID: WP_151185907.1
• Coordinates: 3133582..3133851 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXF61_RS14400	3129098..3130219	+	1122	WP_151185899.1	Fic family protein	-
FXF61_RS14405	3130311..3130775	+	465	WP_151185900.1	bacterioferritin	-
FXF61_RS14410	3130871..3131007	-	137	Protein_2819	phage integrase N-terminal SAM-like domain-containing protein	-
FXF61_RS14415	3131386..3131655	+	270	WP_151185901.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FXF61_RS14420	3131656..3131949	+	294	WP_151185902.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FXF61_RS14425	3132071..3132385	+	315	WP_151185903.1	transcriptional regulator	-
FXF61_RS14430	3132378..3132677	+	300	WP_151185904.1	helix-turn-helix domain-containing protein	-
FXF61_RS14435	3132757..3133257	+	501	WP_151185905.1	GNAT family N-acetyltransferase	-
FXF61_RS14440	3133329..3133592	+	264	WP_151185906.1	BrnT family toxin	Toxin
FXF61_RS14445	3133582..3133851	+	270	WP_151185907.1	CopG family transcriptional regulator	Antitoxin
FXF61_RS14450	3133928..3134185	+	258	WP_151185908.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FXF61_RS14455	3134173..3134475	+	303	WP_151185909.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FXF61_RS14460	3134572..3135369	+	798	WP_151185910.1	PhzF family phenazine biosynthesis protein	-
FXF61_RS14465	3135870..3137372	+	1503	WP_151185911.1	DUF3375 domain-containing protein	-
FXF61_RS14470	3137375..3138079	+	705	WP_151185912.1	DUF4194 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	3132757..3134185	1428

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10277.61 Da
• Isoelectric Point: 6.2410

>T138357 WP_151185906.1 NZ_CP043320:3133329-3133592 [Pseudomonas sp. C27(2019)]
MEEFEFDEAKSQANLDKHGIDFVAAQELWKDPHLLEIRAKSEDEPRFALIGKVGEKHWSAVVTYREGRIRLISVRRSRKK
EVEFYES

Nucleotide

• Length: 264 bp

>T138357 NZ_CP043320:3133329-3133592 [Pseudomonas sp. C27(2019)]
ATGGAAGAATTTGAATTCGACGAAGCCAAAAGTCAGGCAAATCTGGATAAGCACGGTATTGATTTCGTGGCGGCTCAAGA
GCTATGGAAAGATCCGCATTTGCTGGAAATTAGAGCAAAATCAGAGGATGAGCCAAGGTTTGCATTGATAGGCAAGGTTG
GTGAAAAGCACTGGTCGGCTGTCGTCACGTACAGGGAAGGTCGTATTCGTCTGATTTCAGTCAGGCGTTCTCGTAAGAAG
GAGGTTGAGTTCTATGAAAGCTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10135.45 Da
• Isoelectric Point: 5.1847

>AT138357 WP_151185907.1 NZ_CP043320:3133582-3133851 [Pseudomonas sp. C27(2019)]
MKAKDFDKKFDEGQEDIIEDLDLSTARRTNLKQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAETANKPL
NDDAVGGAH

Nucleotide

• Length: 270 bp

>AT138357 NZ_CP057632:704643-704960 [Citrobacter sp. RHB20-C15]
ATGAGCAACACCACATGGGGCCTGCAGCGATATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTGGCTGACCGGGCCAGTATTACCGGTAAATTCAGTGACCCCGAGTGTCTCAAGCTGAATGTAGCATTTCCAC
ATTTTATCAGCCAGTTGGAGTCGATGCTTACCGCTGGTGAAATGAACCCTCGCCATGCCCACTGTGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGCAGTTGCGGCTACGTATACATCGCCATTTACCCCACTCAGCGTTAA