Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2097074..2097630 Replicon chromosome
Accession NZ_CP043320
Organism Pseudomonas sp. C27(2019)

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FXF61_RS09555 Protein ID WP_151185042.1
Coordinates 2097074..2097382 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FXF61_RS09560 Protein ID WP_151185043.1
Coordinates 2097382..2097630 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXF61_RS09520 2092117..2092902 - 786 WP_178087290.1 hypothetical protein -
FXF61_RS09525 2092961..2094037 - 1077 WP_151185036.1 transposase -
FXF61_RS09530 2094239..2094418 - 180 WP_151185037.1 hypothetical protein -
FXF61_RS09540 2094814..2095653 + 840 WP_151185039.1 mechanosensitive ion channel -
FXF61_RS09545 2096014..2096544 - 531 WP_151185040.1 GNAT family N-acetyltransferase -
FXF61_RS09550 2096541..2096810 - 270 WP_151185041.1 DUF1778 domain-containing protein -
FXF61_RS09555 2097074..2097382 - 309 WP_151185042.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXF61_RS09560 2097382..2097630 - 249 WP_151185043.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FXF61_RS09570 2098526..2100106 - 1581 WP_151185044.1 Fic family protein -
FXF61_RS09575 2100385..2102391 - 2007 WP_151185045.1 polysaccharide biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-94)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 12055.66 Da        Isoelectric Point: 8.8780

>T138356 WP_151185042.1 NZ_CP043320:c2097382-2097074 [Pseudomonas sp. C27(2019)]
MQPVRKVRVTPRARDDLKNIGRYTERTWGKAQRNHYLKSLDARFDWLAENPQLGKHRPDICEGYHSFPEGQHVVFYLLDS
RTLDIIGIPHKEMDTISYFQEG

Download         Length: 309 bp

>T138356 NZ_CP043320:c2097382-2097074 [Pseudomonas sp. C27(2019)]
ATGCAGCCCGTAAGAAAAGTCCGGGTGACCCCACGGGCGCGGGACGACCTTAAAAATATTGGTCGCTATACCGAGCGCAC
TTGGGGCAAAGCCCAGCGAAACCACTACTTGAAGAGCCTTGATGCACGTTTTGACTGGCTGGCTGAAAACCCACAACTGG
GAAAGCACCGTCCAGATATCTGCGAGGGATACCACAGCTTCCCTGAAGGTCAGCACGTAGTGTTCTACCTGCTTGACAGT
AGAACCTTAGATATCATCGGCATACCCCACAAGGAAATGGACACCATCAGCTACTTCCAGGAAGGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9062.98 Da        Isoelectric Point: 4.3875

>AT138356 WP_151185043.1 NZ_CP043320:c2097630-2097382 [Pseudomonas sp. C27(2019)]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRAHLSEGANQAKNGEFVDDFSMDSLINDLDA
ES

Download         Length: 249 bp

>AT138356 NZ_CP043320:c2097630-2097382 [Pseudomonas sp. C27(2019)]
ATGGCTACTACCAGTCTAAGTCTGGGTGAGCACTGGGAGGTGTTCATCAAAAATGAAATTTCCAGCGGCCGTTACGGCTC
CGCCAGTGAAGTGGTACGCGATGCCTTGCGCGCCATGGAAGAGCGCAAGAGCAAACTCGAAGCTCTGCGCGCCCACCTGT
CAGAAGGTGCAAACCAAGCCAAAAATGGCGAGTTTGTTGATGACTTTTCAATGGATTCGTTGATCAATGATCTGGATGCT
GAATCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References