Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 2096014..2096810 Replicon chromosome
Accession NZ_CP043320
Organism Pseudomonas sp. C27(2019)

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FXF61_RS09545 Protein ID WP_151185040.1
Coordinates 2096014..2096544 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FXF61_RS09550 Protein ID WP_151185041.1
Coordinates 2096541..2096810 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXF61_RS09520 2092117..2092902 - 786 WP_178087290.1 hypothetical protein -
FXF61_RS09525 2092961..2094037 - 1077 WP_151185036.1 transposase -
FXF61_RS09530 2094239..2094418 - 180 WP_151185037.1 hypothetical protein -
FXF61_RS09540 2094814..2095653 + 840 WP_151185039.1 mechanosensitive ion channel -
FXF61_RS09545 2096014..2096544 - 531 WP_151185040.1 GNAT family N-acetyltransferase Toxin
FXF61_RS09550 2096541..2096810 - 270 WP_151185041.1 DUF1778 domain-containing protein Antitoxin
FXF61_RS09555 2097074..2097382 - 309 WP_151185042.1 type II toxin-antitoxin system RelE/ParE family toxin -
FXF61_RS09560 2097382..2097630 - 249 WP_151185043.1 type II toxin-antitoxin system ParD family antitoxin -
FXF61_RS09570 2098526..2100106 - 1581 WP_151185044.1 Fic family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19650.88 Da        Isoelectric Point: 8.4901

>T138355 WP_151185040.1 NZ_CP043320:c2096544-2096014 [Pseudomonas sp. C27(2019)]
MSWSKTFEELSKSKHDRDSFDCGESELNTFIHTQAAKHMQAGISRTMVLPGTAALINQKYPICAFYSVAPSSICRETLPA
ALAKKLPHYPVPVFLLAQLAVHKAFHGCGLGKVSLIKALEYLWDVNAHMRAYAIVVDCLTDSAQSFYQTFGFQVLCEQNG
RVRMFLPMKTVAQLFT

Download         Length: 531 bp

>T138355 NZ_CP043320:c2096544-2096014 [Pseudomonas sp. C27(2019)]
ATGAGTTGGTCAAAGACGTTTGAAGAACTTAGTAAATCCAAGCATGACCGCGATTCTTTTGATTGTGGTGAGAGTGAGCT
GAATACCTTTATCCATACTCAAGCGGCTAAACATATGCAGGCCGGCATCAGCCGCACAATGGTGTTACCTGGCACTGCAG
CGCTGATCAATCAGAAGTATCCGATCTGTGCGTTTTATAGCGTTGCGCCCAGTTCGATTTGCCGTGAGACATTGCCTGCT
GCATTGGCTAAAAAACTACCGCATTATCCCGTGCCTGTTTTTCTACTGGCTCAGCTAGCTGTTCATAAAGCGTTTCATGG
CTGCGGTCTAGGTAAAGTGAGCCTGATTAAAGCACTAGAATATTTGTGGGATGTGAATGCGCATATGCGAGCATACGCAA
TCGTGGTTGATTGCTTAACGGACTCAGCTCAAAGCTTCTATCAGACGTTTGGGTTTCAAGTGCTATGTGAGCAGAATGGA
CGAGTGCGTATGTTTTTACCCATGAAAACTGTGGCGCAGCTGTTCACTTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9866.24 Da        Isoelectric Point: 4.3023

>AT138355 WP_151185041.1 NZ_CP043320:c2096810-2096541 [Pseudomonas sp. C27(2019)]
MATARLDIRLDEEIKVKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESMTIEDNVFDQFMAACEQAQAPNKALLEAA
AFTKASDFK

Download         Length: 270 bp

>AT138355 NZ_CP057631:c24110-23841 [Citrobacter sp. RHB20-C16]
ATGTCAGCACTGAAAAAACAGCGCATCGATCTCAGATTAACCGACGACGACAAGAGCATGATCGAAGAAGCTGCGGCAAT
GACCAACCAGACAATTACTCAGTTTATGGTTGCCAGTGCCTCTGAACGTGCTGCGGAAGTGATAGAGCAACATCGTCGCC
TGATTCTTAGCGAAGAGTCATGGAATATAGTGATGGATGCCATCAGTAACCCGCCTGCACCGAATGATAGGCTGAAACGA
GCTGCCGAGCGTCTACAAAGCATGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References