Detailed information of TA system TA138330

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 5431582..5432077
• Replicon: chromosome
• Accession: NZ_CP043311
• Organism: Pseudomonas lalkuanensis strain PE08

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: FXN65_RS25070
• Protein ID: WP_151137493.1
• Coordinates: 5431817..5432077 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FXN65_RS25065
• Protein ID: WP_151137491.1
• Coordinates: 5431582..5431827 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXN65_RS25035	5426969..5427667	+	699	WP_151137481.1	urea ABC transporter ATP-binding subunit UrtE	-
FXN65_RS25040	5427690..5428529	+	840	WP_151137483.1	urease accessory protein UreD	-
FXN65_RS25045	5428529..5428831	+	303	WP_151137485.1	urease subunit gamma	-
FXN65_RS25050	5428910..5429404	+	495	WP_151138957.1	GNAT family N-acetyltransferase	-
FXN65_RS25055	5429409..5429714	+	306	WP_151137487.1	urease subunit beta	-
FXN65_RS25060	5429792..5431492	+	1701	WP_151137489.1	urease subunit alpha	-
FXN65_RS25065	5431582..5431827	+	246	WP_151137491.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FXN65_RS25070	5431817..5432077	+	261	WP_151137493.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FXN65_RS25075	5432120..5432386	-	267	WP_151137494.1	DksA/TraR family C4-type zinc finger protein	-
FXN65_RS25080	5432484..5433350	-	867	WP_178119398.1	oxaloacetate decarboxylase	-
FXN65_RS25085	5433538..5433984	+	447	WP_151137498.1	DedA family protein	-
FXN65_RS25090	5434206..5434559	+	354	WP_151137500.1	hypothetical protein	-
FXN65_RS25095	5434567..5435049	+	483	WP_151137502.1	hypothetical protein	-
FXN65_RS25100	5435139..5435408	-	270	WP_151137504.1	phosphate starvation-inducible protein PsiF	-
FXN65_RS25105	5435527..5436792	+	1266	WP_151137506.1	Hsp70 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-67)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10037.77 Da
• Isoelectric Point: 11.1724

>T138330 WP_151137493.1 NZ_CP043311:5431817-5432077 [Pseudomonas lalkuanensis]
MTYELEFLPSARKEWRKLGDTVREQFRKKLKERLQRQLIQGDALHGMPERFKIKLRTAGYRLVDRVEDQRITVVVIGVGK
RAGGAV

Nucleotide

• Length: 261 bp

>T138330 NZ_CP043311:5431817-5432077 [Pseudomonas lalkuanensis]
ATGACCTATGAACTGGAGTTCCTGCCCTCGGCGCGGAAGGAGTGGCGCAAGCTCGGCGATACCGTCCGGGAGCAATTCAG
GAAGAAGCTGAAAGAGCGGCTGCAACGGCAGCTGATCCAGGGCGATGCACTTCACGGGATGCCCGAGCGATTCAAGATCA
AACTCCGCACCGCCGGTTATCGCCTGGTGGATCGGGTGGAAGACCAACGCATCACTGTGGTGGTGATCGGCGTTGGCAAA
CGCGCAGGTGGTGCGGTCTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8574.91 Da
• Isoelectric Point: 6.4570

>AT138330 WP_151137491.1 NZ_CP043311:5431582-5431827 [Pseudomonas lalkuanensis]
MQSVLANGAVSVSALKKNPSAVVSGAKGAPVAVLNHNKVMAYMVSAETFEALMEYLDDQALAEIVRSRAHEKGMKVSLDD
L

Nucleotide

• Length: 246 bp

>AT138330 NZ_CP043311:5431582-5431827 [Pseudomonas lalkuanensis]
TTGCAAAGCGTACTGGCCAATGGTGCTGTCAGCGTTTCCGCGCTGAAGAAAAATCCCTCTGCCGTGGTGTCCGGCGCCAA
GGGTGCGCCTGTGGCTGTTCTCAACCACAACAAGGTCATGGCCTACATGGTTTCGGCTGAAACCTTCGAAGCACTGATGG
AGTATCTGGACGATCAGGCGCTGGCCGAAATCGTCCGCAGCCGTGCCCACGAGAAGGGAATGAAAGTCAGCCTCGATGAC
CTATGA