Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 5431582..5432077 Replicon chromosome
Accession NZ_CP043311
Organism Pseudomonas lalkuanensis strain PE08

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag FXN65_RS25070 Protein ID WP_151137493.1
Coordinates 5431817..5432077 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXN65_RS25065 Protein ID WP_151137491.1
Coordinates 5431582..5431827 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN65_RS25035 5426969..5427667 + 699 WP_151137481.1 urea ABC transporter ATP-binding subunit UrtE -
FXN65_RS25040 5427690..5428529 + 840 WP_151137483.1 urease accessory protein UreD -
FXN65_RS25045 5428529..5428831 + 303 WP_151137485.1 urease subunit gamma -
FXN65_RS25050 5428910..5429404 + 495 WP_151138957.1 GNAT family N-acetyltransferase -
FXN65_RS25055 5429409..5429714 + 306 WP_151137487.1 urease subunit beta -
FXN65_RS25060 5429792..5431492 + 1701 WP_151137489.1 urease subunit alpha -
FXN65_RS25065 5431582..5431827 + 246 WP_151137491.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXN65_RS25070 5431817..5432077 + 261 WP_151137493.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXN65_RS25075 5432120..5432386 - 267 WP_151137494.1 DksA/TraR family C4-type zinc finger protein -
FXN65_RS25080 5432484..5433350 - 867 WP_178119398.1 oxaloacetate decarboxylase -
FXN65_RS25085 5433538..5433984 + 447 WP_151137498.1 DedA family protein -
FXN65_RS25090 5434206..5434559 + 354 WP_151137500.1 hypothetical protein -
FXN65_RS25095 5434567..5435049 + 483 WP_151137502.1 hypothetical protein -
FXN65_RS25100 5435139..5435408 - 270 WP_151137504.1 phosphate starvation-inducible protein PsiF -
FXN65_RS25105 5435527..5436792 + 1266 WP_151137506.1 Hsp70 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10037.77 Da        Isoelectric Point: 11.1724

>T138330 WP_151137493.1 NZ_CP043311:5431817-5432077 [Pseudomonas lalkuanensis]
MTYELEFLPSARKEWRKLGDTVREQFRKKLKERLQRQLIQGDALHGMPERFKIKLRTAGYRLVDRVEDQRITVVVIGVGK
RAGGAV

Download         Length: 261 bp

>T138330 NZ_CP043311:5431817-5432077 [Pseudomonas lalkuanensis]
ATGACCTATGAACTGGAGTTCCTGCCCTCGGCGCGGAAGGAGTGGCGCAAGCTCGGCGATACCGTCCGGGAGCAATTCAG
GAAGAAGCTGAAAGAGCGGCTGCAACGGCAGCTGATCCAGGGCGATGCACTTCACGGGATGCCCGAGCGATTCAAGATCA
AACTCCGCACCGCCGGTTATCGCCTGGTGGATCGGGTGGAAGACCAACGCATCACTGTGGTGGTGATCGGCGTTGGCAAA
CGCGCAGGTGGTGCGGTCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8574.91 Da        Isoelectric Point: 6.4570

>AT138330 WP_151137491.1 NZ_CP043311:5431582-5431827 [Pseudomonas lalkuanensis]
MQSVLANGAVSVSALKKNPSAVVSGAKGAPVAVLNHNKVMAYMVSAETFEALMEYLDDQALAEIVRSRAHEKGMKVSLDD
L

Download         Length: 246 bp

>AT138330 NZ_CP043311:5431582-5431827 [Pseudomonas lalkuanensis]
TTGCAAAGCGTACTGGCCAATGGTGCTGTCAGCGTTTCCGCGCTGAAGAAAAATCCCTCTGCCGTGGTGTCCGGCGCCAA
GGGTGCGCCTGTGGCTGTTCTCAACCACAACAAGGTCATGGCCTACATGGTTTCGGCTGAAACCTTCGAAGCACTGATGG
AGTATCTGGACGATCAGGCGCTGGCCGAAATCGTCCGCAGCCGTGCCCACGAGAAGGGAATGAAAGTCAGCCTCGATGAC
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References