Detailed information of TA system TA138329

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 1239187..1240601
• Replicon: chromosome
• Accession: NZ_CP043311
• Organism: Pseudomonas lalkuanensis strain PE08

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FXN65_RS05890
• Protein ID: WP_151132155.1
• Coordinates: 1239187..1239756 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FXN65_RS05895
• Protein ID: WP_151132156.1
• Coordinates: 1239759..1240601 (+)
• Length: 281 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXN65_RS05880	1234926..1235345	+	420	WP_151138673.1	hypothetical protein	-
FXN65_RS05885	1235456..1238935	-	3480	WP_151132154.1	hybrid sensor histidine kinase/response regulator	-
FXN65_RS05890	1239187..1239756	+	570	WP_151132155.1	GNAT family N-acetyltransferase	Toxin
FXN65_RS05895	1239759..1240601	+	843	WP_151132156.1	AraC family transcriptional regulator	Antitoxin
FXN65_RS05900	1240638..1241369	+	732	WP_151132157.1	AzlC family ABC transporter permease	-
FXN65_RS05905	1241351..1241680	+	330	WP_151132158.1	AzlD domain-containing protein	-
FXN65_RS05910	1241903..1243777	+	1875	WP_151132159.1	MFS transporter	-
FXN65_RS05915	1243822..1244136	-	315	WP_151132160.1	quaternary ammonium compound efflux SMR transporter SugE	-
FXN65_RS05920	1244316..1245236	-	921	WP_151132161.1	recombination-associated protein RdgC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (194-271)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21343.46 Da
• Isoelectric Point: 8.5300

>T138329 WP_151132155.1 NZ_CP043311:1239187-1239756 [Pseudomonas lalkuanensis]
MFNPQPVTLQRGALRLEPLMEADIPALVTLAEANREVLVYMNGPLRPDWYRQALAAQREGRAVVFAIRLGDNLVGTTRFA
DFMPSLPAAEIGWTWLAAGEHGSGLNASIKYLMLRHAFEEWQLVRVQLKTAASNLRSQRAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHDWPEVRQRLEALFSA

Nucleotide

• Length: 570 bp

>T138329 NZ_CP057566:81978-82130 [Escherichia fergusonii]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGTACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin

Protein

• Length: 281 a.a.
• Molecular weight: 31338.49 Da
• Isoelectric Point: 7.7446

>AT138329 WP_151132156.1 NZ_CP043311:1239759-1240601 [Pseudomonas lalkuanensis]
VSEQREDAHFWQAGHLDGLELLSARYIEHRFAPHVHDGYVIAVVEAGAERYRYRGVDHLAGAGSLALINPDEVHTGSKGH
DDGWRYRVFYPDVALVRSALEELELPLAGMPAFIGSVHHDPDLVRMFTHLHRLLEANASALEQQTAWREALLALFRRHSR
LPEPGAPGREPLAVLHAKELLRERLAEPPSLEELASAVRLSPFHFARTFRRSTGMPPHAWLKQQRLDQARALLRAGCTPA
GVAAQLGFADQSHLTRQFKQAYGVGPGEYRNACARSFKTH

Nucleotide

• Length: 843 bp

>AT138329 NZ_CP057566:c81928-81866 [Escherichia fergusonii]
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT