138325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 5889..6402 Replicon plasmid pAcsw19-3
Accession NZ_CP043310
Organism Acinetobacter johnsonii strain Acsw19

Toxin (Protein)


Gene name yoeB Uniprot ID N8YGB2
Locus tag FYN22_RS18315 Protein ID WP_000184943.1
Coordinates 5889..6152 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N8ZW56
Locus tag FYN22_RS18320 Protein ID WP_000557944.1
Coordinates 6139..6402 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYN22_RS18290 1070..1501 + 432 WP_148827140.1 hypothetical protein -
FYN22_RS18295 1734..2020 - 287 Protein_2 hypothetical protein -
FYN22_RS18300 2017..2959 - 943 Protein_3 replication initiation protein -
FYN22_RS18305 3668..5313 - 1646 Protein_4 MobA/MobL family protein -
FYN22_RS18310 5525..5827 + 303 WP_000110201.1 hypothetical protein -
FYN22_RS18315 5889..6152 - 264 WP_000184943.1 Txe/YoeB family addiction module toxin Toxin
FYN22_RS18320 6139..6402 - 264 WP_000557944.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FYN22_RS18325 6538..7017 - 480 WP_065995571.1 cysteine hydrolase family protein -
FYN22_RS18330 8301..8540 - 240 WP_148827141.1 hypothetical protein -
FYN22_RS18335 8799..9155 + 357 Protein_10 hypothetical protein -
FYN22_RS18340 9418..9706 - 289 Protein_11 hypothetical protein -
FYN22_RS18345 9703..10644 - 942 WP_020846814.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..38391 38391


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10649.09 Da        Isoelectric Point: 8.4866

>T138325 WP_000184943.1 NZ_CP043310:c6152-5889 [Acinetobacter johnsonii]
MTNRNVEWTDNAWDEYIYWQTQDKKILKRINTLIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T138325 NZ_CP043310:c6152-5889 [Acinetobacter johnsonii]
ATGACGAATCGTAACGTCGAATGGACTGATAATGCCTGGGATGAATATATCTATTGGCAGACACAGGATAAAAAGATACT
TAAGCGTATTAATACCTTAATCAAAGAATGTCAGCGAACACCTTTTGAAGGAACAGGAAAACCAGAACCTTTAAAAGCTA
ATCTTTCAGGATTTTGGAGTCGTAGGATTGATGAAAAGCATAGATTAGTTTATGAAGTGACAGATGAACGAATCTCTATA
ATTCAATGTCGATTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9834.99 Da        Isoelectric Point: 5.0829

>AT138325 WP_000557944.1 NZ_CP043310:c6402-6139 [Acinetobacter johnsonii]
MHVFTYTDARNNLKSVLDKVIDDVDVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNASRLNESIAQLRAGKTKHRE
LIEDDES

Download         Length: 264 bp

>AT138325 NZ_CP043310:c6402-6139 [Acinetobacter johnsonii]
ATGCATGTATTTACATATACGGACGCACGTAACAATTTAAAATCTGTTTTAGATAAAGTAATTGATGATGTAGACGTTGC
TTTTATTACAAGAAAAGAAGGTGGCCATGCTGTAGTAATGGGACAAGATCATTATGATAGCTTAATGGAAACGTTATATC
TCCTTTCATCTCCAAATAATGCAAGTCGTTTAAATGAATCAATTGCTCAATTACGTGCAGGGAAAACAAAACACAGAGAG
TTGATTGAGGATGACGAATCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6C0XPS2

Antitoxin

Source ID Structure
AlphaFold DB A0A6C0XPU2

References