Detailed information of TA system TA138321

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 403309..403946
• Replicon: chromosome
• Accession: NZ_CP043307
• Organism: Acinetobacter johnsonii strain Acsw19

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: FYN22_RS01920
• Protein ID: WP_148825442.1
• Coordinates: 403560..403946 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: FYN22_RS01915
• Protein ID: WP_171065375.1
• Coordinates: 403309..403554 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FYN22_RS01895	398916..399281	+	366	WP_004691290.1	50S ribosomal protein L17	-
FYN22_RS01900	399477..400967	+	1491	WP_148825439.1	NAD(P)/FAD-dependent oxidoreductase	-
FYN22_RS01905	401105..401896	+	792	WP_148825440.1	alpha/beta hydrolase	-
FYN22_RS01910	401932..403104	-	1173	WP_148825441.1	acyl-CoA dehydrogenase family protein	-
FYN22_RS01915	403309..403554	+	246	WP_171065375.1	succinate dehydrogenase assembly factor 2	Antitoxin
FYN22_RS01920	403560..403946	+	387	WP_148825442.1	hypothetical protein	Toxin
FYN22_RS01925	404467..405504	+	1038	WP_148825443.1	hypothetical protein	-
FYN22_RS01930	405576..406148	+	573	WP_148825444.1	rhombosortase	-
FYN22_RS01935	406331..408613	+	2283	WP_148825445.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-127)

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15316.35 Da
• Isoelectric Point: 10.5476

>T138321 WP_148825442.1 NZ_CP043307:403560-403946 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPLGLWLIALVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSLQKKTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T138321 NZ_CP057565:1911022-1911125 [Escherichia fergusonii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9691.18 Da
• Isoelectric Point: 5.1473

>AT138321 WP_171065375.1 NZ_CP043307:403309-403554 [Acinetobacter johnsonii]
MSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT138321 NZ_CP057565:c1911163-1910896 [Escherichia fergusonii]
AAAGTCAGCGAATGGAATATTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCGT
TCTGGTGAAAGAACTGAGGCGGTTTTTT