Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002082..2002353 Replicon chromosome
Accession NZ_CP043274
Organism Escherichia coli strain WCHEC035148

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002212..2002315 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002082..2002353 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYK53_RS09705 1998637..1999299 - 663 WP_000944256.1 exodeoxyribonuclease X -
FYK53_RS09710 1999323..1999979 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
FYK53_RS09715 2000081..2000311 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FYK53_RS09720 2000450..2000824 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FYK53_RS09725 2000828..2001700 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
FYK53_RS09730 2001713..2002054 + 342 WP_000976492.1 YebY family protein -
- 2002082..2002353 - 272 - - Antitoxin
- 2002212..2002315 + 104 - - Toxin
FYK53_RS09735 2002450..2003106 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FYK53_RS09740 2003107..2003298 - 192 WP_001296140.1 YebW family protein -
FYK53_RS09745 2003403..2003639 - 237 WP_001295499.1 YebV family protein -
FYK53_RS09750 2003757..2005196 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1948551..2018191 69640


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T138171 NZ_CP043274:2002212-2002315 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT138171 NZ_CP043274:c2002353-2002082 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References