Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4421192..4421787 Replicon chromosome
Accession NZ_CP043271
Organism Escherichia albertii strain RM9973

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag FYK17_RS21065 Protein ID WP_085455822.1
Coordinates 4421437..4421787 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag FYK17_RS21060 Protein ID WP_059255553.1
Coordinates 4421192..4421443 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYK17_RS21050 4416857..4420636 + 3780 WP_207610366.1 translocation/assembly module TamB domain-containing protein -
FYK17_RS21055 4420639..4420983 + 345 WP_001219163.1 gamma-glutamylcyclotransferase -
FYK17_RS21060 4421192..4421443 + 252 WP_059255553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FYK17_RS21065 4421437..4421787 + 351 WP_085455822.1 type II toxin-antitoxin system ChpB family toxin Toxin
FYK17_RS21070 4421840..4423219 - 1380 WP_207610367.1 sugar porter family MFS transporter -
FYK17_RS21075 4423232..4423732 - 501 WP_085455824.1 D-ribose pyranase -
FYK17_RS21080 4423818..4425200 - 1383 WP_085455825.1 sugar porter family MFS transporter -
FYK17_RS21085 4425214..4426182 - 969 WP_085455826.1 1-phosphofructokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-115)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12661.68 Da        Isoelectric Point: 5.1420

>T138150 WP_085455822.1 NZ_CP043271:4421437-4421787 [Escherichia albertii]
MVKRSEFERGDIMLVGFDPTSGHEQRGAGRPVLVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLRCEEGDVCGVVVV
NQVRMMDLNARQAKRIGLACDEVVEEVLLRLQAVVE

Download         Length: 351 bp

>T138150 NZ_CP043271:4421437-4421787 [Escherichia albertii]
ATGGTGAAGCGAAGTGAATTTGAACGGGGAGACATTATGCTGGTTGGCTTTGATCCAACAAGCGGCCATGAACAGCGAGG
TGCTGGTCGACCTGTGCTTGTACTCTCCGTTCAAGCCTTTAATCAACTGGGGATGACGCTGGTAGCCCCCATTACTCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCGTTACGTTGTGAAGAAGGCGATGTGTGTGGCGTGGTGGTGGTG
AATCAGGTACGAATGATGGATTTAAATGCCCGGCAGGCAAAGCGTATTGGTCTGGCTTGCGACGAGGTGGTGGAAGAGGT
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9237.69 Da        Isoelectric Point: 4.9431

>AT138150 WP_059255553.1 NZ_CP043271:4421192-4421443 [Escherichia albertii]
MRITIKKWGNSAGMVIPNIVMKGLKLQPGQSLEAQVRNNQLILTPVSKRYSLDELLAQCDMNAPELSEQDVWGTLSPAGD
EIW

Download         Length: 252 bp

>AT138150 NZ_CP057313:c5069184-5068942 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCACGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References