Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3939736..3940007 Replicon chromosome
Accession NZ_CP043197
Organism Escherichia coli O16:H48 strain PG20180061

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3939866..3939969 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3939736..3940007 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYA12_RS19040 3936291..3936953 - 663 WP_000944256.1 exodeoxyribonuclease X -
FYA12_RS19045 3936977..3937633 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FYA12_RS19050 3937735..3937965 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FYA12_RS19055 3938104..3938478 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FYA12_RS19060 3938482..3939354 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FYA12_RS19065 3939367..3939708 + 342 WP_000976476.1 YebY family protein -
- 3939736..3940007 - 272 - - Antitoxin
- 3939866..3939969 + 104 - - Toxin
FYA12_RS19070 3940104..3940760 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FYA12_RS19075 3940761..3940952 - 192 WP_000457842.1 YebW family protein -
FYA12_RS19080 3941057..3941293 - 237 WP_001295499.1 DUF1480 family protein -
FYA12_RS19085 3941411..3942850 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T137634 NZ_CP043197:3939866-3939969 [Escherichia coli O16:H48]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT137634 NZ_CP043197:c3940007-3939736 [Escherichia coli O16:H48]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References