Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959990..1960261 Replicon chromosome
Accession NZ_CP043193
Organism Escherichia coli O16:H48 strain PG20180063

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960120..1960223 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959990..1960261 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYA14_RS09390 1956545..1957207 - 663 WP_000944256.1 exodeoxyribonuclease X -
FYA14_RS09395 1957231..1957887 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FYA14_RS09400 1957989..1958219 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FYA14_RS09405 1958358..1958732 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FYA14_RS09410 1958736..1959608 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FYA14_RS09415 1959621..1959962 + 342 WP_000976476.1 YebY family protein -
- 1959990..1960261 - 272 - - Antitoxin
- 1960120..1960223 + 104 - - Toxin
FYA14_RS09420 1960358..1961014 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FYA14_RS09425 1961015..1961206 - 192 WP_000457842.1 YebW family protein -
FYA14_RS09430 1961311..1961547 - 237 WP_001295499.1 DUF1480 family protein -
FYA14_RS09435 1961665..1963104 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T137563 NZ_CP043193:1960120-1960223 [Escherichia coli O16:H48]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT137563 NZ_CP043193:c1960261-1959990 [Escherichia coli O16:H48]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References