Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959989..1960260 Replicon chromosome
Accession NZ_CP043183
Organism Escherichia coli O16:H48 strain PG20180172

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960119..1960222 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959989..1960260 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYA19_RS09390 1956544..1957206 - 663 WP_000944256.1 exodeoxyribonuclease X -
FYA19_RS09395 1957230..1957886 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FYA19_RS09400 1957988..1958218 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FYA19_RS09405 1958357..1958731 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FYA19_RS09410 1958735..1959607 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FYA19_RS09415 1959620..1959961 + 342 WP_000976476.1 YebY family protein -
- 1959989..1960260 - 272 - - Antitoxin
- 1960119..1960222 + 104 - - Toxin
FYA19_RS09420 1960357..1961013 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FYA19_RS09425 1961014..1961205 - 192 WP_000457842.1 YebW family protein -
FYA19_RS09430 1961310..1961546 - 237 WP_001295499.1 DUF1480 family protein -
FYA19_RS09435 1961664..1963103 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T137402 NZ_CP043183:1960119-1960222 [Escherichia coli O16:H48]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT137402 NZ_CP043183:c1960260-1959989 [Escherichia coli O16:H48]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References