Detailed information of TA system TA137033

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 5329712..5330604
• Replicon: chromosome
• Accession: NZ_CP043056
• Organism: Dolichospermum sp. UHCC 0315A

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: BMF77_RS25155
• Protein ID: WP_148766665.1
• Coordinates: 5329712..5330155 (-)
• Length: 148 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: BMF77_RS25160
• Protein ID: WP_148766667.1
• Coordinates: 5330152..5330604 (-)
• Length: 151 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BMF77_RS25145	5325221..5326264	-	1044	WP_148766661.1	type I-D CRISPR-associated protein Cas7/Csc2	-
BMF77_RS25150	5326357..5329719	-	3363	WP_148766663.1	type I-D CRISPR-associated protein Cas10d/Csc3	-
BMF77_RS25155	5329712..5330155	-	444	WP_148766665.1	DUF86 domain-containing protein	Toxin
BMF77_RS25160	5330152..5330604	-	453	WP_148766667.1	nucleotidyltransferase domain-containing protein	Antitoxin
BMF77_RS25165	5330709..5330915	-	207	WP_148766669.1	hypothetical protein	-
BMF77_RS25170	5331359..5332678	-	1320	Protein_4915	type I-D CRISPR-associated helicase Cas3'	-
BMF77_RS25175	5332745..5333634	+	890	Protein_4916	IS630 family transposase	-
BMF77_RS25180	5333854..5334177	+	324	Protein_4917	DUF4277 domain-containing protein	-
BMF77_RS25185	5334380..5335269	-	890	Protein_4918	IS630 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (17-133)

Antitoxin

• Polymerase beta, nucleotidyltransferase (16-112)

Sequences

Toxin

Protein

• Length: 148 a.a.
• Molecular weight: 16982.40 Da
• Isoelectric Point: 4.5034

>T137033 WP_148766665.1 NZ_CP043056:c5330155-5329712 [Dolichospermum sp. UHCC 0315A]
MNNLDPEIVLARLKLIAKYYNTLEEFRSISLDEFLADFRQQLIVERLLQLMTQAAIDINDHILSKLNSGKSYTNFEAFIE
LGNSQIITPELAKQIAPSSGLRNRLVHEYDDIDPKQVFMAINFALQQYPLYVRQINSYLISLEEDNG

Nucleotide

• Length: 444 bp

>T137033 NZ_CP043056:c5330155-5329712 [Dolichospermum sp. UHCC 0315A]
ATGAATAATCTAGACCCAGAAATAGTTTTAGCTAGACTAAAGCTCATTGCCAAATATTACAATACTTTAGAAGAATTTCG
TTCTATTAGTCTTGATGAATTTTTAGCTGATTTTCGTCAACAGCTTATTGTAGAAAGATTGCTGCAATTAATGACTCAAG
CAGCGATAGACATCAACGACCATATATTGTCAAAGCTAAACTCTGGAAAATCCTATACTAATTTTGAGGCTTTCATTGAA
TTAGGTAACTCTCAAATAATTACACCAGAATTAGCGAAACAAATAGCACCATCATCGGGATTAAGGAATCGGTTAGTTCA
TGAATATGATGATATAGATCCCAAGCAAGTTTTTATGGCAATTAATTTTGCTTTACAGCAATATCCGCTTTATGTTAGAC
AAATTAACTCTTACTTAATTTCATTGGAAGAAGACAATGGCTAA

Antitoxin

Protein

• Length: 151 a.a.
• Molecular weight: 17446.92 Da
• Isoelectric Point: 5.0206

>AT137033 WP_148766667.1 NZ_CP043056:c5330604-5330152 [Dolichospermum sp. UHCC 0315A]
MENNTPTITELQKLSSQFTEKIPYLKMLVLFGSRATDKTNINSDWDFAVLCDEKQRQSYIENNMSGLFELPILIGEVLKI
NPDIIDTVELNQCSWLIAHFVARDGISLFEKHPGEFDNFRLNSVKTQSELKKFRQEQHRIIEIELNKWGA

Nucleotide

• Length: 453 bp

>AT137033 NZ_CP056422:37868-38137 [Citrobacter sp. RHBSTW-00524]
ATGTCAGCACTGAAAAAACAGCGCATCGATCTAAGATTAACTGACGACGACAAGAGCATGATCGAAGAAGCTGCGGCAAT
GACCAACCAGACTATTACTCAGTTTATGGTTGCCAGCGCCTCTGAACGTGCTGCGGAAGTGATAGAGCAACATCGCCGCT
TGATTCTCAGTGAAGAGTCCTGGAATCTGGTAATGGATGCCATCAGTAACCCGCCTGCACCGAACGATAGGCTGAAACGA
GCTGCCAAACGTCTACAAAGCATGGAGTAA