137031

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2642383..2643088 Replicon chromosome
Accession NZ_CP043056
Organism Dolichospermum sp. UHCC 0315A

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag BMF77_RS12800 Protein ID WP_148763264.1
Coordinates 2642711..2643088 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag BMF77_RS12795 Protein ID WP_137908399.1
Coordinates 2642383..2642706 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BMF77_RS12770 2637441..2637665 + 225 WP_148763256.1 type II toxin-antitoxin system HicB family antitoxin -
BMF77_RS12775 2637658..2637903 + 246 WP_148763258.1 type II toxin-antitoxin system HicA family toxin -
BMF77_RS12785 2638313..2641519 + 3207 WP_148763260.1 glycoside hydrolase family 15 protein -
BMF77_RS12790 2641606..2642268 - 663 WP_148763262.1 response regulator transcription factor -
BMF77_RS12795 2642383..2642706 - 324 WP_137908399.1 helix-turn-helix domain-containing protein Antitoxin
BMF77_RS12800 2642711..2643088 - 378 WP_148763264.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BMF77_RS12805 2643286..2643729 - 444 WP_168204433.1 type II toxin-antitoxin system VapC family toxin -
BMF77_RS12810 2643726..2643962 - 237 WP_148763268.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
BMF77_RS12815 2644218..2644865 - 648 WP_148763270.1 hypothetical protein -
BMF77_RS12820 2645059..2645418 + 360 WP_148763272.1 hypothetical protein -
BMF77_RS12825 2645477..2646394 + 918 WP_148763274.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-89)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14336.42 Da        Isoelectric Point: 7.5178

>T137031 WP_148763264.1 NZ_CP043056:c2643088-2642711 [Dolichospermum sp. UHCC 0315A]
MNEKQEKPLRWIASALHDLKKFPEDVQDVMGYALDLAQHGQKHPNAKPLHGFSGAGVLEIVDDFDGDTYRAIYTVKFEGV
IYLLHSFQKKSKHGIATPKQDIELVKKRLKIAQENYLQQTTEKME

Download         Length: 378 bp

>T137031 NZ_CP056421:c5077310-5076999 [Citrobacter sp. RHBSTW-00524]
ATGCTATTCATAGAAACGGAAATCTTCACTGAAGACGTCAAAAAATTACTGGATGATGATGAATACCGTAGATTACAGAT
ATTCCTTGCGATTCAGCCCGATTGTGGCGATCTAATACAAGAAACGGGGGGCCTGAGAAAGGTTCGCTGGAGAGCGCGAG
GGAAAGGAAAACGTGGTGGTGTGAGGATTATCTATTTTCATCAAATCAGGGAATCACAAATTCGATTGTTGCTGATTTAT
CAGAAAGGGATTAAGGATGATCTGACTCCGCAAGAAAAAGTACTGCTGCGTATGTTGAATGAGAGGTGGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11903.76 Da        Isoelectric Point: 4.8660

>AT137031 WP_137908399.1 NZ_CP043056:c2642706-2642383 [Dolichospermum sp. UHCC 0315A]
MPEENQVEVSSGNVFADLGLSNPEERLLKAELVRKISEIITNLNLTQVQAAEILGIDQPKVSLLIRGRLSGFSTDRLMDY
LNKLGSDVEITVKPKPENRKFAQIIVV

Download         Length: 324 bp

>AT137031 NZ_CP056421:c5076998-5076711 [Citrobacter sp. RHBSTW-00524]
ATGGATAAGGCACTATTTGAGCGACTAACTCAAAGTATGGTTCAGATGAATGAGATCGCTGAAGGAACACGGCAACCTTC
CCGTACCTTTCATATTGATGCCATGAAAATAAAGGAAATCCGCCTGTCTTCAGGATTATCACAGACTCGTTTCGCAGATT
TGATATCGGTAAGCGTGGATACGTTGCGCAATTGGGAGCAGGGGCGTCGTTCACCGACTGGTCCAGCAAAAGCGTTGTTA
CGTGCTATTGCCAATGATCCAAAACATGTCATTCAGGCGCTAAGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References