Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tad-ata/COG5606-COG4679 |
| Location | 2642383..2643088 | Replicon | chromosome |
| Accession | NZ_CP043056 | ||
| Organism | Dolichospermum sp. UHCC 0315A | ||
Toxin (Protein)
| Gene name | tad | Uniprot ID | - |
| Locus tag | BMF77_RS12800 | Protein ID | WP_148763264.1 |
| Coordinates | 2642711..2643088 (-) | Length | 126 a.a. |
Antitoxin (Protein)
| Gene name | ata | Uniprot ID | - |
| Locus tag | BMF77_RS12795 | Protein ID | WP_137908399.1 |
| Coordinates | 2642383..2642706 (-) | Length | 108 a.a. |
Genomic Context
Location: 2637441..2637665 (225 bp)
Type: Others
Protein ID: WP_148763256.1
Type: Others
Protein ID: WP_148763256.1
Location: 2637658..2637903 (246 bp)
Type: Others
Protein ID: WP_148763258.1
Type: Others
Protein ID: WP_148763258.1
Location: 2638313..2641519 (3207 bp)
Type: Others
Protein ID: WP_148763260.1
Type: Others
Protein ID: WP_148763260.1
Location: 2645059..2645418 (360 bp)
Type: Others
Protein ID: WP_148763272.1
Type: Others
Protein ID: WP_148763272.1
Location: 2645477..2646394 (918 bp)
Type: Others
Protein ID: WP_148763274.1
Type: Others
Protein ID: WP_148763274.1
Location: 2641606..2642268 (663 bp)
Type: Others
Protein ID: WP_148763262.1
Type: Others
Protein ID: WP_148763262.1
Location: 2642383..2642706 (324 bp)
Type: Antitoxin
Protein ID: WP_137908399.1
Type: Antitoxin
Protein ID: WP_137908399.1
Location: 2642711..2643088 (378 bp)
Type: Toxin
Protein ID: WP_148763264.1
Type: Toxin
Protein ID: WP_148763264.1
Location: 2643286..2643729 (444 bp)
Type: Others
Protein ID: WP_168204433.1
Type: Others
Protein ID: WP_168204433.1
Location: 2643726..2643962 (237 bp)
Type: Others
Protein ID: WP_148763268.1
Type: Others
Protein ID: WP_148763268.1
Location: 2644218..2644865 (648 bp)
Type: Others
Protein ID: WP_148763270.1
Type: Others
Protein ID: WP_148763270.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BMF77_RS12770 | 2637441..2637665 | + | 225 | WP_148763256.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| BMF77_RS12775 | 2637658..2637903 | + | 246 | WP_148763258.1 | type II toxin-antitoxin system HicA family toxin | - |
| BMF77_RS12785 | 2638313..2641519 | + | 3207 | WP_148763260.1 | glycoside hydrolase family 15 protein | - |
| BMF77_RS12790 | 2641606..2642268 | - | 663 | WP_148763262.1 | response regulator transcription factor | - |
| BMF77_RS12795 | 2642383..2642706 | - | 324 | WP_137908399.1 | helix-turn-helix domain-containing protein | Antitoxin |
| BMF77_RS12800 | 2642711..2643088 | - | 378 | WP_148763264.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| BMF77_RS12805 | 2643286..2643729 | - | 444 | WP_168204433.1 | type II toxin-antitoxin system VapC family toxin | - |
| BMF77_RS12810 | 2643726..2643962 | - | 237 | WP_148763268.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| BMF77_RS12815 | 2644218..2644865 | - | 648 | WP_148763270.1 | hypothetical protein | - |
| BMF77_RS12820 | 2645059..2645418 | + | 360 | WP_148763272.1 | hypothetical protein | - |
| BMF77_RS12825 | 2645477..2646394 | + | 918 | WP_148763274.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 14336.42 Da Isoelectric Point: 7.5178
>T137031 WP_148763264.1 NZ_CP043056:c2643088-2642711 [Dolichospermum sp. UHCC 0315A]
MNEKQEKPLRWIASALHDLKKFPEDVQDVMGYALDLAQHGQKHPNAKPLHGFSGAGVLEIVDDFDGDTYRAIYTVKFEGV
IYLLHSFQKKSKHGIATPKQDIELVKKRLKIAQENYLQQTTEKME
MNEKQEKPLRWIASALHDLKKFPEDVQDVMGYALDLAQHGQKHPNAKPLHGFSGAGVLEIVDDFDGDTYRAIYTVKFEGV
IYLLHSFQKKSKHGIATPKQDIELVKKRLKIAQENYLQQTTEKME
Download Length: 378 bp
>T137031 NZ_CP056421:c5077310-5076999 [Citrobacter sp. RHBSTW-00524]
ATGCTATTCATAGAAACGGAAATCTTCACTGAAGACGTCAAAAAATTACTGGATGATGATGAATACCGTAGATTACAGAT
ATTCCTTGCGATTCAGCCCGATTGTGGCGATCTAATACAAGAAACGGGGGGCCTGAGAAAGGTTCGCTGGAGAGCGCGAG
GGAAAGGAAAACGTGGTGGTGTGAGGATTATCTATTTTCATCAAATCAGGGAATCACAAATTCGATTGTTGCTGATTTAT
CAGAAAGGGATTAAGGATGATCTGACTCCGCAAGAAAAAGTACTGCTGCGTATGTTGAATGAGAGGTGGTAA
ATGCTATTCATAGAAACGGAAATCTTCACTGAAGACGTCAAAAAATTACTGGATGATGATGAATACCGTAGATTACAGAT
ATTCCTTGCGATTCAGCCCGATTGTGGCGATCTAATACAAGAAACGGGGGGCCTGAGAAAGGTTCGCTGGAGAGCGCGAG
GGAAAGGAAAACGTGGTGGTGTGAGGATTATCTATTTTCATCAAATCAGGGAATCACAAATTCGATTGTTGCTGATTTAT
CAGAAAGGGATTAAGGATGATCTGACTCCGCAAGAAAAAGTACTGCTGCGTATGTTGAATGAGAGGTGGTAA
Antitoxin
Download Length: 108 a.a. Molecular weight: 11903.76 Da Isoelectric Point: 4.8660
>AT137031 WP_137908399.1 NZ_CP043056:c2642706-2642383 [Dolichospermum sp. UHCC 0315A]
MPEENQVEVSSGNVFADLGLSNPEERLLKAELVRKISEIITNLNLTQVQAAEILGIDQPKVSLLIRGRLSGFSTDRLMDY
LNKLGSDVEITVKPKPENRKFAQIIVV
MPEENQVEVSSGNVFADLGLSNPEERLLKAELVRKISEIITNLNLTQVQAAEILGIDQPKVSLLIRGRLSGFSTDRLMDY
LNKLGSDVEITVKPKPENRKFAQIIVV
Download Length: 324 bp
>AT137031 NZ_CP056421:c5076998-5076711 [Citrobacter sp. RHBSTW-00524]
ATGGATAAGGCACTATTTGAGCGACTAACTCAAAGTATGGTTCAGATGAATGAGATCGCTGAAGGAACACGGCAACCTTC
CCGTACCTTTCATATTGATGCCATGAAAATAAAGGAAATCCGCCTGTCTTCAGGATTATCACAGACTCGTTTCGCAGATT
TGATATCGGTAAGCGTGGATACGTTGCGCAATTGGGAGCAGGGGCGTCGTTCACCGACTGGTCCAGCAAAAGCGTTGTTA
CGTGCTATTGCCAATGATCCAAAACATGTCATTCAGGCGCTAAGATAA
ATGGATAAGGCACTATTTGAGCGACTAACTCAAAGTATGGTTCAGATGAATGAGATCGCTGAAGGAACACGGCAACCTTC
CCGTACCTTTCATATTGATGCCATGAAAATAAAGGAAATCCGCCTGTCTTCAGGATTATCACAGACTCGTTTCGCAGATT
TGATATCGGTAAGCGTGGATACGTTGCGCAATTGGGAGCAGGGGCGTCGTTCACCGACTGGTCCAGCAAAAGCGTTGTTA
CGTGCTATTGCCAATGATCCAAAACATGTCATTCAGGCGCTAAGATAA