Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 2518423..2519000 Replicon chromosome
Accession NZ_CP043056
Organism Dolichospermum sp. UHCC 0315A

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag BMF77_RS12210 Protein ID WP_148763104.1
Coordinates 2518423..2518683 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag BMF77_RS12215 Protein ID WP_148763106.1
Coordinates 2518671..2519000 (+) Length 110 a.a.

Genomic Context

BMF77_RS12185BMF77_RS12210BMF77_RS12215BMF77_RS12190BMF77_RS12195BMF77_RS12200BMF77_RS12205BMF77_RS12220BMF77_RS12225BMF77_RS12230
Location: 2515387..2516475 (1089 bp)
Type: Others
Protein ID: WP_148763094.1
Location: 2518423..2518683 (261 bp)
Type: Toxin
Protein ID: WP_148763104.1
Location: 2518671..2519000 (330 bp)
Type: Antitoxin
Protein ID: WP_148763106.1
Location: 2516529..2516921 (393 bp)
Type: Others
Protein ID: WP_148763096.1
Location: 2516911..2517138 (228 bp)
Type: Others
Protein ID: WP_148763098.1
Location: 2517524..2518009 (486 bp)
Type: Others
Protein ID: WP_148763100.1
Location: 2518015..2518254 (240 bp)
Type: Others
Protein ID: WP_148763102.1
Location: 2519121..2521901 (2781 bp)
Type: Others
Protein ID: WP_148763109.1
Location: 2522043..2522579 (537 bp)
Type: Others
Protein ID: Protein_2376
Location: 2522714..2523478 (765 bp)
Type: Others
Protein ID: WP_148763111.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BMF77_RS121852515387..2516475+1089WP_148763094.1hypothetical protein-
BMF77_RS121902516529..2516921-393WP_148763096.1type II toxin-antitoxin system VapC family toxin-
BMF77_RS121952516911..2517138-228WP_148763098.1hypothetical protein-
BMF77_RS122002517524..2518009-486WP_148763100.1DUF3368 domain-containing protein-
BMF77_RS122052518015..2518254-240WP_148763102.1UPF0175 family protein-
BMF77_RS122102518423..2518683+261WP_148763104.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinToxin
BMF77_RS122152518671..2519000+330WP_148763106.1type II toxin-antitoxin system PemK/MazF family toxinAntitoxin
BMF77_RS122202519121..2521901-2781WP_148763109.1preprotein translocase subunit SecA-
BMF77_RS122252522043..2522579-537Protein_2376cytochrome C-
BMF77_RS122302522714..2523478-765WP_148763111.1flagellar motor protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(10-52)

Antitoxin

mRNA interferase PemK-like

(7-107)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9955.34 Da        Isoelectric Point: 4.8430

>T137029 WP_148763104.1 NZ_CP043056:2518423-2518683 [Dolichospermum sp. UHCC 0315A]
MGTAIKTRIVKIGNSQGLRIPKTLLEQSGINSEVEIEVHGNHLIIRPVTQIRKGWEKAFIEMAEKQDDVLLDDINTTEWD
KDEWQW

Download         Length: 261 bp

>T137029 NZ_CP043056:2518423-2518683 [Dolichospermum sp. UHCC 0315A]
ATGGGTACAGCAATTAAAACCAGAATAGTCAAAATCGGCAATTCCCAAGGTTTACGCATTCCCAAAACCTTATTAGAACA
AAGCGGAATTAACTCAGAAGTAGAAATAGAAGTTCACGGTAATCATCTGATTATTCGCCCAGTTACACAAATAAGAAAAG
GTTGGGAAAAAGCATTTATAGAAATGGCAGAAAAACAAGATGATGTCCTATTAGATGATATCAACACAACAGAATGGGAT
AAAGATGAATGGCAATGGTAG

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12235.33 Da        Isoelectric Point: 7.1338

>AT137029 WP_148763106.1 NZ_CP043056:2518671-2519000 [Dolichospermum sp. UHCC 0315A]
MAMVVNRFDVFLVNLDPTIGSEIKKTRPCLIISPNEINHHIATVIVAPMTTKGQPYPTRVTCQFQGQNGQIVLDQIRTVD
KTRLVKLLGQITTEEQKTVLDILAEMFAE

Download         Length: 330 bp

>AT137029 NZ_CP043056:2518671-2519000 [Dolichospermum sp. UHCC 0315A]
ATGGCAATGGTAGTTAACAGATTTGATGTTTTCCTAGTTAATCTTGACCCTACCATTGGGAGTGAAATTAAAAAAACACG
CCCCTGCTTAATAATTTCACCAAACGAGATAAACCACCATATTGCCACCGTCATAGTTGCACCAATGACAACAAAAGGGC
AACCATACCCCACAAGAGTAACCTGTCAATTTCAAGGACAAAATGGACAAATTGTATTAGACCAAATTCGCACAGTAGAT
AAAACTCGATTAGTCAAACTTCTGGGTCAAATTACTACAGAAGAACAAAAAACAGTTCTGGATATCCTAGCTGAAATGTT
CGCCGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References