Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1306179..1306871 Replicon chromosome
Accession NZ_CP043056
Organism Dolichospermum sp. UHCC 0315A

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag BMF77_RS05965 Protein ID WP_148761411.1
Coordinates 1306611..1306871 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag BMF77_RS05960 Protein ID WP_148761409.1
Coordinates 1306179..1306517 (-) Length 113 a.a.

Genomic Context

BMF77_RS05935BMF77_RS05940BMF77_RS05950BMF77_RS05975BMF77_RS05980BMF77_RS06005BMF77_RS06010BMF77_RS06015BMF77_RS06020BMF77_RS05955BMF77_RS05960BMF77_RS05965BMF77_RS05970BMF77_RS05985BMF77_RS05990BMF77_RS05995BMF77_RS06025
Location: 1301413..1302504 (1092 bp)
Type: Others
Protein ID: WP_148761401.1
Location: 1302686..1303567 (882 bp)
Type: Others
Protein ID: WP_148761403.1
Location: 1303967..1305073 (1107 bp)
Type: Others
Protein ID: WP_148761405.1
Location: 1307574..1307825 (252 bp)
Type: Others
Protein ID: WP_148761413.1
Location: 1307828..1307983 (156 bp)
Type: Others
Protein ID: WP_148761415.1
Location: 1309238..1309453 (216 bp)
Type: Others
Protein ID: Protein_1182
Location: 1309589..1309888 (300 bp)
Type: Others
Protein ID: WP_148761425.1
Location: 1309885..1310085 (201 bp)
Type: Others
Protein ID: WP_148761427.1
Location: 1310308..1310766 (459 bp)
Type: Others
Protein ID: WP_148761429.1
Location: 1305469..1306062 (594 bp)
Type: Others
Protein ID: WP_148761407.1
Location: 1306179..1306517 (339 bp)
Type: Antitoxin
Protein ID: WP_148761409.1
Location: 1306611..1306871 (261 bp)
Type: Toxin
Protein ID: WP_148761411.1
Location: 1307220..1307438 (219 bp)
Type: Others
Protein ID: WP_210422304.1
Location: 1308025..1308336 (312 bp)
Type: Others
Protein ID: WP_148761417.1
Location: 1308413..1308691 (279 bp)
Type: Others
Protein ID: WP_148761419.1
Location: 1308966..1309178 (213 bp)
Type: Others
Protein ID: WP_148761421.1
Location: 1310690..1311601 (912 bp)
Type: Others
Protein ID: WP_148761431.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BMF77_RS059351301413..1302504+1092WP_148761401.1spermidine/putrescine ABC transporter substrate-binding protein-
BMF77_RS059401302686..1303567+882WP_148761403.1ABC transporter permease-
BMF77_RS059501303967..1305073+1107WP_148761405.1Gfo/Idh/MocA family oxidoreductase-
BMF77_RS059551305469..1306062-594WP_148761407.1hypothetical protein-
BMF77_RS059601306179..1306517-339WP_148761409.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
BMF77_RS059651306611..1306871-261WP_148761411.1type II toxin-antitoxin system HicA family toxinToxin
BMF77_RS059701307220..1307438-219WP_210422304.1cobaltochelatase subunit CobN-
BMF77_RS059751307574..1307825+252WP_148761413.1type II toxin-antitoxin system ParD family antitoxin-
BMF77_RS059801307828..1307983+156WP_148761415.1type II toxin-antitoxin system RelE/ParE family toxin-
BMF77_RS059851308025..1308336-312WP_148761417.1HigA family addiction module antidote protein-
BMF77_RS059901308413..1308691-279WP_148761419.1type II toxin-antitoxin system RelE/ParE family toxin-
BMF77_RS059951308966..1309178-213WP_148761421.1type II toxin-antitoxin system HicB family antitoxin-
BMF77_RS060051309238..1309453+216Protein_1182type II toxin-antitoxin system Phd/YefM family antitoxin-
BMF77_RS060101309589..1309888+300WP_148761425.1BrnT family toxin-
BMF77_RS060151309885..1310085+201WP_148761427.1hypothetical protein-
BMF77_RS060201310308..1310766+459WP_148761429.1DUF1848 family protein-
BMF77_RS060251310690..1311601-912WP_148761431.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(25-83)

Antitoxin

Uncharacterised protein family HicB

(52-102)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9643.00 Da        Isoelectric Point: 8.6585

>T137028 WP_148761411.1 NZ_CP043056:c1306871-1306611 [Dolichospermum sp. UHCC 0315A]
MDLNNKQRKTLELIFTNPVPANIIWQDIESLFIALGAYISQGSGSRVGVKLNDVKGHFHEPHPHKETDKGTVKSVREFLT
KAGFEP

Download         Length: 261 bp

>T137028 NZ_CP043056:c1306871-1306611 [Dolichospermum sp. UHCC 0315A]
ATGGATCTCAACAATAAACAAAGAAAAACTTTAGAATTAATTTTTACAAATCCTGTACCAGCAAATATTATTTGGCAAGA
TATTGAAAGTCTATTTATAGCTTTAGGTGCTTATATTAGTCAAGGTAGCGGTTCAAGAGTAGGAGTTAAATTAAATGATG
TTAAAGGTCATTTTCATGAACCACATCCCCATAAAGAAACAGATAAAGGAACTGTTAAATCTGTACGTGAATTTTTGACA
AAAGCAGGATTTGAACCATAA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12543.41 Da        Isoelectric Point: 5.7723

>AT137028 WP_148761409.1 NZ_CP043056:c1306517-1306179 [Dolichospermum sp. UHCC 0315A]
MLTYKGYTASIEVDVEAGILFGRVLDINDVVTFKAKTVEEARQEFETSIDGYLAFCKELGEEPDKPFSGKLPFRTTPEHH
RKIFIAAKKAGKSINAWMDEMLINAAEKSVKA

Download         Length: 339 bp

>AT137028 NZ_CP056421:c3109379-3109077 [Citrobacter sp. RHBSTW-00524]
ATGGGCAGAACGCTGGAACAGCTTATTGCGGATGAAAAACCTGAAGTCGTGGCCGAAGCTCAGGCGATGGCGACGGACAT
CCTGCTCAACATTCACCTTGCCGAACTGCGCGAGAAAGTGCAGAGAACGCAGGTCGAAATGGCGAAGGCGCTGGGGATCA
GGCAACCTACCGTTGCAGGAATGGAAAAACCGGGGCGCGACCTGAAGCTTTCCACGCTGAAACGCTACGTTGAAGCGACC
GGCGGCAAGCTACGCCTTGATATTGAACTGCCGGATGGTTCTCACTACGGATTTGTACTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References