Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 832314..832914 | Replicon | chromosome |
Accession | NZ_CP043056 | ||
Organism | Dolichospermum sp. UHCC 0315A |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BMF77_RS03840 | Protein ID | WP_148760782.1 |
Coordinates | 832314..832667 (-) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | BMF77_RS03845 | Protein ID | WP_148760784.1 |
Coordinates | 832660..832914 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BMF77_RS03820 | 828198..829490 | - | 1293 | WP_148760778.1 | ferredoxin:protochlorophyllide reductase (ATP-dependent) subunit N | - |
BMF77_RS03825 | 829834..830889 | - | 1056 | WP_148760779.1 | tRNA 2-thiouridine(34) synthase MnmA | - |
BMF77_RS03830 | 831101..831646 | + | 546 | WP_148760780.1 | photosystem II reaction center PsbP family protein | - |
BMF77_RS03835 | 831717..832310 | + | 594 | WP_148760781.1 | septum formation inhibitor Maf | - |
BMF77_RS03840 | 832314..832667 | - | 354 | WP_148760782.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BMF77_RS03845 | 832660..832914 | - | 255 | WP_148760784.1 | hypothetical protein | Antitoxin |
BMF77_RS03850 | 833193..833957 | + | 765 | WP_148760786.1 | phycocyanobilin:ferredoxin oxidoreductase | - |
BMF77_RS03855 | 834478..835896 | + | 1419 | WP_148760787.1 | biotin/lipoyl-binding protein | - |
BMF77_RS03860 | 835966..837120 | + | 1155 | WP_148760790.1 | ABC transporter permease DevC | - |
BMF77_RS26485 | 837140..837274 | - | 135 | Protein_760 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 13465.51 Da Isoelectric Point: 7.9624
>T137026 WP_148760782.1 NZ_CP043056:c832667-832314 [Dolichospermum sp. UHCC 0315A]
MSDIPFIQVEVTLRFQRNLRKLAKKYLKIHNDIQPVIEQLQQGERLGDCIPKIGYEVFKLRVKNSDTQKGKSGGYRLIYY
VKTATAIILLTIYAKSEQADIAPDDIQSIISEYESED
MSDIPFIQVEVTLRFQRNLRKLAKKYLKIHNDIQPVIEQLQQGERLGDCIPKIGYEVFKLRVKNSDTQKGKSGGYRLIYY
VKTATAIILLTIYAKSEQADIAPDDIQSIISEYESED
Download Length: 354 bp
>T137026 NZ_CP043056:c832667-832314 [Dolichospermum sp. UHCC 0315A]
ATGTCTGATATCCCATTTATTCAAGTAGAAGTAACACTAAGATTTCAGCGAAATTTACGTAAACTAGCCAAGAAATATCT
AAAGATTCACAATGATATTCAACCAGTTATAGAACAACTACAACAAGGAGAAAGACTCGGTGATTGCATTCCTAAAATCG
GTTATGAAGTTTTCAAATTGCGCGTCAAAAATAGCGACACTCAAAAAGGTAAAAGTGGTGGTTATCGTCTCATTTACTAT
GTCAAAACTGCAACAGCTATTATTTTGCTAACCATTTATGCAAAATCTGAACAAGCTGATATTGCCCCAGATGATATCCA
AAGTATTATTTCTGAATATGAATCTGAAGATTGA
ATGTCTGATATCCCATTTATTCAAGTAGAAGTAACACTAAGATTTCAGCGAAATTTACGTAAACTAGCCAAGAAATATCT
AAAGATTCACAATGATATTCAACCAGTTATAGAACAACTACAACAAGGAGAAAGACTCGGTGATTGCATTCCTAAAATCG
GTTATGAAGTTTTCAAATTGCGCGTCAAAAATAGCGACACTCAAAAAGGTAAAAGTGGTGGTTATCGTCTCATTTACTAT
GTCAAAACTGCAACAGCTATTATTTTGCTAACCATTTATGCAAAATCTGAACAAGCTGATATTGCCCCAGATGATATCCA
AAGTATTATTTCTGAATATGAATCTGAAGATTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9548.87 Da Isoelectric Point: 4.4258
>AT137026 WP_148760784.1 NZ_CP043056:c832914-832660 [Dolichospermum sp. UHCC 0315A]
MKAIKVMATVNQQGSLSLDKPLNIIQNSRVEVIILIPEAVEINEDHEQISSKEEIIQDFRQSWHEAMTGHTIPVSQLWEG
IENV
MKAIKVMATVNQQGSLSLDKPLNIIQNSRVEVIILIPEAVEINEDHEQISSKEEIIQDFRQSWHEAMTGHTIPVSQLWEG
IENV
Download Length: 255 bp
>AT137026 NZ_CP043056:c832914-832660 [Dolichospermum sp. UHCC 0315A]
ATGAAAGCAATTAAAGTCATGGCAACCGTTAATCAACAAGGAAGTTTGTCCTTAGATAAACCATTAAATATTATTCAAAA
TAGCCGTGTAGAAGTTATTATTCTTATTCCAGAAGCAGTAGAAATTAACGAAGATCATGAACAAATTTCATCTAAAGAAG
AAATAATTCAAGATTTTCGTCAGTCTTGGCACGAAGCAATGACTGGACACACAATTCCTGTTTCTCAACTTTGGGAAGGA
ATTGAAAATGTCTGA
ATGAAAGCAATTAAAGTCATGGCAACCGTTAATCAACAAGGAAGTTTGTCCTTAGATAAACCATTAAATATTATTCAAAA
TAGCCGTGTAGAAGTTATTATTCTTATTCCAGAAGCAGTAGAAATTAACGAAGATCATGAACAAATTTCATCTAAAGAAG
AAATAATTCAAGATTTTCGTCAGTCTTGGCACGAAGCAATGACTGGACACACAATTCCTGTTTCTCAACTTTGGGAAGGA
ATTGAAAATGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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