Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 122961..123532 Replicon chromosome
Accession NZ_CP043056
Organism Dolichospermum sp. UHCC 0315A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BMF77_RS00615 Protein ID WP_148759831.1
Coordinates 122961..123302 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BMF77_RS00620 Protein ID WP_148759833.1
Coordinates 123299..123532 (-) Length 78 a.a.

Genomic Context

BMF77_RS00605BMF77_RS00610BMF77_RS00625BMF77_RS00635BMF77_RS00640BMF77_RS00650BMF77_RS00655BMF77_RS00660BMF77_RS00580BMF77_RS00585BMF77_RS00590BMF77_RS00595BMF77_RS00600BMF77_RS00615BMF77_RS00620BMF77_RS00630
Location: 119821..120738 (918 bp)
Type: Others
Protein ID: WP_148759827.1
Location: 120938..122620 (1683 bp)
Type: Others
Protein ID: WP_148759829.1
Location: 123553..123753 (201 bp)
Type: Others
Protein ID: Protein_121
Location: 125666..125888 (223 bp)
Type: Others
Protein ID: Protein_123
Location: 126073..126435 (363 bp)
Type: Others
Protein ID: WP_015078221.1
Location: 127226..127447 (222 bp)
Type: Others
Protein ID: WP_015078220.1
Location: 127447..128079 (633 bp)
Type: Others
Protein ID: WP_015078219.1
Location: 128086..128511 (426 bp)
Type: Others
Protein ID: WP_015078218.1
Location: 118278..118496 (219 bp)
Type: Others
Protein ID: WP_210422273.1
Location: 118564..118731 (168 bp)
Type: Others
Protein ID: WP_148759825.1
Location: 118721..118951 (231 bp)
Type: Others
Protein ID: WP_137908734.1
Location: 119031..119405 (375 bp)
Type: Others
Protein ID: WP_210422274.1
Location: 119395..119643 (249 bp)
Type: Others
Protein ID: WP_053541040.1
Location: 122961..123302 (342 bp)
Type: Toxin
Protein ID: WP_148759831.1
Location: 123299..123532 (234 bp)
Type: Antitoxin
Protein ID: WP_148759833.1
Location: 123880..125616 (1737 bp)
Type: Others
Protein ID: WP_148759835.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BMF77_RS00580118278..118496-219WP_210422273.1hypothetical protein-
BMF77_RS00585118564..118731-168WP_148759825.1type II toxin-antitoxin system PemK/MazF family toxin-
BMF77_RS00590118721..118951-231WP_137908734.1hypothetical protein-
BMF77_RS00595119031..119405-375WP_210422274.1putative toxin-antitoxin system toxin component, PIN family-
BMF77_RS00600119395..119643-249WP_053541040.1hypothetical protein-
BMF77_RS00605119821..120738+918WP_148759827.1hypothetical protein-
BMF77_RS00610120938..122620+1683WP_148759829.1hypothetical protein-
BMF77_RS00615122961..123302-342WP_148759831.1DUF5615 family PIN-like proteinToxin
BMF77_RS00620123299..123532-234WP_148759833.1DUF433 domain-containing proteinAntitoxin
BMF77_RS00625123553..123753+201Protein_121hypothetical protein-
BMF77_RS00630123880..125616-1737WP_148759835.1GTPase HflX-
BMF77_RS00635125666..125888+223Protein_123hypothetical protein-
BMF77_RS00640126073..126435+363WP_015078221.150S ribosomal protein L19-
BMF77_RS00650127226..127447+222WP_015078220.1preprotein translocase subunit SecE-
BMF77_RS00655127447..128079+633WP_015078219.1transcription termination/antitermination protein NusG-
BMF77_RS00660128086..128511+426WP_015078218.150S ribosomal protein L11-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(11-66)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12737.92 Da        Isoelectric Point: 4.3063

>T137025 WP_148759831.1 NZ_CP043056:c123302-122961 [Dolichospermum sp. UHCC 0315A]
MKIWIDAQLPATLAIWVTDTFAIEAFSLRDIGLRDAKDIEIFEAAKIANVIIMTKDSDFVDLVCRLGIPPQILWLTCGNV
TNRNLRQLLIITLPDALEQLQQGEMIVEISNSR

Download         Length: 342 bp

>T137025 NZ_CP043056:c123302-122961 [Dolichospermum sp. UHCC 0315A]
ATGAAAATTTGGATTGATGCACAGTTACCAGCAACATTGGCAATTTGGGTAACAGATACTTTTGCTATAGAAGCATTTTC
ATTAAGAGATATTGGGTTACGTGATGCTAAAGATATAGAAATTTTTGAAGCTGCAAAAATCGCTAATGTCATCATCATGA
CGAAAGACAGTGATTTTGTTGATTTGGTTTGTCGGTTAGGAATACCTCCTCAAATCCTTTGGTTAACTTGTGGAAATGTG
ACGAATCGCAATCTGCGTCAACTTCTGATCATTACTTTACCTGATGCTTTGGAACAATTACAGCAAGGAGAAATGATTGT
GGAAATCAGCAATAGTCGGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8662.01 Da        Isoelectric Point: 4.3466

>AT137025 WP_148759833.1 NZ_CP043056:c123532-123299 [Dolichospermum sp. UHCC 0315A]
INSMNELLNRITQIPGQCGGRPCIRGMRIRVSDILEMLAENVSVSEILEDFPDLEPEDIQACLVFAARRTDFVRLTA

Download         Length: 234 bp

>AT137025 NZ_CP043056:c123532-123299 [Dolichospermum sp. UHCC 0315A]
ATTAACTCAATGAACGAATTATTAAATCGGATTACGCAAATTCCTGGTCAATGTGGGGGTCGTCCTTGCATTCGCGGAAT
GAGAATTAGAGTTAGCGACATTTTAGAAATGTTAGCCGAAAATGTCAGCGTTAGCGAAATTTTAGAAGACTTTCCCGATT
TAGAACCAGAAGATATTCAAGCTTGTCTTGTGTTTGCTGCACGACGGACTGATTTTGTCCGGTTAACAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References