Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4216775..4217569 Replicon chromosome
Accession NZ_CP043046
Organism Pigmentiphaga aceris strain Mada1488

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag FXN63_RS18250 Protein ID WP_148816607.1
Coordinates 4216775..4217275 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag FXN63_RS18255 Protein ID WP_148819538.1
Coordinates 4217279..4217569 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN63_RS18225 4212685..4214001 - 1317 WP_148816604.1 aspartate aminotransferase family protein -
FXN63_RS18230 4214171..4215580 + 1410 WP_148816605.1 PLP-dependent aminotransferase family protein -
FXN63_RS18235 4215583..4216278 + 696 WP_148816606.1 hypothetical protein -
FXN63_RS18240 4216357..4216637 - 281 Protein_3597 XRE family transcriptional regulator -
FXN63_RS18250 4216775..4217275 - 501 WP_148816607.1 GNAT family N-acetyltransferase Toxin
FXN63_RS18255 4217279..4217569 - 291 WP_148819538.1 DUF1778 domain-containing protein Antitoxin
FXN63_RS18260 4217629..4218063 - 435 WP_148816608.1 DUF3325 domain-containing protein -
FXN63_RS18265 4218060..4218362 - 303 WP_148816609.1 DUF3649 domain-containing protein -
FXN63_RS18270 4218359..4220065 - 1707 WP_148816610.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-140)

Antitoxin

Vibrio phage ICP1, Orf50

(1-94)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 17512.26 Da        Isoelectric Point: 7.3844

>T136996 WP_148816607.1 NZ_CP043046:c4217275-4216775 [Pigmentiphaga aceris]
MLLAPVPLDSGHDTHDFDCGVESLNAWLIRRALTNQVSGASRTFVVCEGGKLVGYYALASSAVVPAAAPGRFRRNMPDPV
PVVVLGRLAVAVSHRGKGLGRALFQDAALRVIHAADAIGIRGMVVHALSEEAKLFYQNLGLDESPLDPMTLMVTVADLRA
ASGQAV

Download         Length: 501 bp

>T136996 NZ_CP043046:c4217275-4216775 [Pigmentiphaga aceris]
ATGCTGCTTGCCCCGGTACCGCTTGACTCGGGTCACGACACCCACGATTTCGACTGCGGCGTGGAATCTCTCAATGCCTG
GCTGATACGCCGTGCCCTAACTAATCAAGTCAGCGGTGCATCCCGTACCTTCGTGGTCTGCGAGGGCGGCAAGCTTGTGG
GGTACTACGCACTGGCTTCCAGCGCCGTGGTGCCAGCTGCCGCTCCAGGGCGTTTTCGACGCAACATGCCTGACCCCGTG
CCCGTGGTGGTACTGGGTCGTTTGGCGGTTGCGGTCAGTCACCGTGGAAAGGGACTTGGCCGCGCGCTTTTTCAGGATGC
CGCGCTTCGCGTTATCCACGCGGCAGACGCAATCGGCATTCGCGGCATGGTAGTACATGCGCTATCTGAGGAGGCCAAGC
TTTTTTATCAAAATCTTGGTCTGGACGAGTCGCCGCTTGATCCGATGACGCTGATGGTCACTGTTGCCGATCTGCGAGCT
GCAAGCGGGCAGGCCGTGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10794.31 Da        Isoelectric Point: 10.2614

>AT136996 WP_148819538.1 NZ_CP043046:c4217569-4217279 [Pigmentiphaga aceris]
MSTASTTKVPRDTLNLRIPAAERNLIDRAAESAGKTRTDFILEAARRAAEETLLDRALMVVSPEAYEDFLKRLDQPAQPN
ERLRKTLQSKTPWKAA

Download         Length: 291 bp

>AT136996 NZ_CP043046:c4217569-4217279 [Pigmentiphaga aceris]
ATGAGCACCGCCAGCACCACCAAAGTCCCTCGTGACACACTGAATCTGCGGATTCCTGCAGCCGAGCGCAACTTGATCGA
TCGCGCAGCGGAGTCTGCAGGCAAGACGCGCACAGATTTCATTCTCGAAGCGGCGCGCCGTGCCGCTGAAGAAACGCTTC
TGGACCGTGCCCTGATGGTCGTCAGTCCCGAGGCATACGAAGACTTTTTAAAGCGGCTTGATCAGCCTGCTCAGCCCAAT
GAGCGACTGCGCAAGACCCTGCAAAGCAAGACGCCCTGGAAGGCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References