Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 541442..542077 Replicon chromosome
Accession NZ_CP043043
Organism Gluconobacter thailandicus strain HD924

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FXF46_RS02630 Protein ID WP_148619479.1
Coordinates 541442..541852 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FXF46_RS02635 Protein ID WP_148619481.1
Coordinates 541853..542077 (-) Length 75 a.a.

Genomic Context

FXF46_RS02625FXF46_RS02645FXF46_RS02630FXF46_RS02635FXF46_RS02650
Location: 538582..541230 (2649 bp)
Type: Others
Protein ID: WP_148619477.1
Location: 542397..543267 (871 bp)
Type: Others
Protein ID: Protein_499
Location: 541442..541852 (411 bp)
Type: Toxin
Protein ID: WP_148619479.1
Location: 541853..542077 (225 bp)
Type: Antitoxin
Protein ID: WP_148619481.1
Location: 543478..546054 (2577 bp)
Type: Others
Protein ID: WP_148619482.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FXF46_RS02625538582..541230+2649WP_148619477.1hypothetical protein-
FXF46_RS02630541442..541852-411WP_148619479.1tRNA(fMet)-specific endonuclease VapCToxin
FXF46_RS02635541853..542077-225WP_148619481.1antitoxinAntitoxin
FXF46_RS02645542397..543267+871Protein_499integrase core domain-containing protein-
FXF46_RS02650543478..546054-2577WP_148619482.1TonB-dependent receptor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--542397..542834437


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(9-55)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15423.67 Da        Isoelectric Point: 7.2163

>T136991 WP_148619479.1 NZ_CP043043:c541852-541442 [Gluconobacter thailandicus]
MLRYLLDTNLCIRVLRDRPQGLRPRFNSCAEELCISDVVLYELLYGAERSSDPVRTRREVEHFAARLAVLPFDSEAAAHT
ADIRAALERNGRIIGPYDLMIAGHARSRGLIVVTGNLREFQRVEGLRTEDWLTGTV

Download         Length: 411 bp

>T136991 NZ_CP043043:c541852-541442 [Gluconobacter thailandicus]
ATGCTGCGTTACCTACTGGATACGAACCTCTGTATCCGGGTGTTGCGGGATCGACCACAGGGGCTGCGTCCGAGATTCAA
CAGCTGTGCGGAGGAACTCTGCATCTCGGACGTGGTTCTGTATGAACTGCTTTATGGCGCGGAGCGCTCGTCTGATCCTG
TGCGCACCAGACGCGAGGTTGAGCACTTCGCGGCAAGGCTGGCAGTCCTGCCATTCGACAGTGAAGCGGCTGCCCATACA
GCGGATATTCGGGCTGCTCTTGAACGGAATGGCCGTATCATAGGTCCATATGATCTCATGATTGCCGGGCATGCCCGGAG
CAGGGGGCTGATTGTGGTGACCGGGAACCTTCGGGAATTCCAGCGGGTGGAGGGTCTTCGGACGGAGGATTGGCTGACTG
GCACGGTCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8279.46 Da        Isoelectric Point: 5.0181

>AT136991 WP_148619481.1 NZ_CP043043:c542077-541853 [Gluconobacter thailandicus]
MLTRTTLFLSNRSQAVRLPKMVAFGEQVREVVIVSEGSRRIIAPADAAWDDFFAAPGVELGERNQPAMQEREAF

Download         Length: 225 bp

>AT136991 NZ_CP056395:c2426554-2426258 [Citrobacter freundii]
ATGGAGAAACTTATGCAAACCAGCGCTCGTAAGCCAACTCGCGATAAGCAAATTAATATCCGCGCTACTGATGAGGAACG
CGCAGTGATTGATTATGCCGCAAGTTTGGTTAATAAAAACCGCACTGACTTTATCATTGAGAAGGCCGTGCATGAGGCCC
AGAATATCATTCTGGATCAGCGTGTGTTCGTCCTGGACGATGCCCGATATCAGTCTTTCATTGAGCAGCTTGAAGCGCCT
GTACAAAATGTTGAGGGGCGTCAACGCCTGATGGATGTGAAGCCAGAATGGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References