Detailed information of TA system TA136989

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-RelB
• Location: 3410762..3411287
• Replicon: chromosome
• Accession: NZ_CP043042
• Organism: Marinobacter fonticola strain CS412

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FXO11_RS15230
• Protein ID: WP_148863776.1
• Coordinates: 3411015..3411287 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FXO11_RS15225
• Protein ID: WP_148863775.1
• Coordinates: 3410762..3411034 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXO11_RS15185	3406180..3406572	+	393	WP_148863769.1	RidA family protein	-
FXO11_RS15190	3406577..3406915	-	339	WP_148863770.1	hypothetical protein	-
FXO11_RS15195	3407514..3408974	+	1461	WP_168203182.1	diguanylate cyclase	-
FXO11_RS15205	3409248..3409550	-	303	WP_148863772.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FXO11_RS15210	3409538..3409795	-	258	WP_022992576.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FXO11_RS15215	3410043..3410237	+	195	WP_148863773.1	type II toxin-antitoxin system VapB family antitoxin	-
FXO11_RS15220	3410234..3410635	+	402	WP_148863774.1	PIN domain nuclease	-
FXO11_RS15225	3410762..3411034	+	273	WP_148863775.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FXO11_RS15230	3411015..3411287	+	273	WP_148863776.1	Txe/YoeB family addiction module toxin	Toxin
FXO11_RS15235	3411355..3411945	-	591	WP_148863777.1	HEPN domain-containing protein	-
FXO11_RS15240	3412325..3413416	-	1092	WP_148863778.1	TOBE-like domain-containing protein	-
FXO11_RS15245	3413426..3414256	-	831	WP_148863779.1	sulfate ABC transporter permease subunit CysW	-
FXO11_RS15250	3414260..3415132	-	873	WP_148863780.1	sulfate/thiosulfate ABC transporter permease CysT	-
FXO11_RS15255	3415151..3416188	-	1038	WP_148863781.1	thiosulfate ABC transporter substrate-binding protein CysP	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3403032..3411945	8913

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (4-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10719.31 Da
• Isoelectric Point: 10.2218

>T136989 WP_148863776.1 NZ_CP043042:3411015-3411287 [Marinobacter fonticola]
MRSLVFEGNTWEAYEKMREKDQRLHKALRKLLKEMLRSEDPSAGIGKPEPLKHNLSGLWSRRISQKDRLIYRFDDRSIYI
FAIGGHYDQP

Nucleotide

• Length: 273 bp

>T136989 NZ_CP056395:621022-621306 [Citrobacter freundii]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACAGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATTGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGCTATCGTCTGGTGTACCAGGTTCGGGATGAAGTTGTGATTGTGTTTGTTGTCGCGGTAGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10411.66 Da
• Isoelectric Point: 4.6627

>AT136989 WP_148863775.1 NZ_CP043042:3410762-3411034 [Marinobacter fonticola]
MDIISVNKFRDNLKSLVEQVISRHEPLKVTRRAGEAFVIMSAEDWEREQETLHVLQNRDLMQQIAASIDTHSRSQGYTPD
DEQMNEITGI

Nucleotide

• Length: 273 bp

>AT136989 NZ_CP056395:620790-621032 [Citrobacter freundii]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGATAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCAGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGATA
GTGAAGATGCACTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA