136936

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 920784..921438 Replicon chromosome
Accession NZ_CP043009
Organism Citrobacter portucalensis strain WCHCP085039

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FXN82_RS05215 Protein ID WP_003825515.1
Coordinates 921031..921438 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FXN82_RS05210 Protein ID WP_003825514.1
Coordinates 920784..921050 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN82_RS05180 915940..917373 - 1434 WP_079938634.1 6-phospho-beta-glucosidase BglA -
FXN82_RS05185 917494..918222 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
FXN82_RS05190 918275..918586 + 312 WP_148361500.1 N(4)-acetylcytidine aminohydrolase -
FXN82_RS05195 918750..919412 + 663 WP_063940912.1 hemolysin III family protein -
FXN82_RS05200 919543..920526 - 984 WP_148361501.1 tRNA-modifying protein YgfZ -
FXN82_RS05210 920784..921050 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
FXN82_RS05215 921031..921438 + 408 WP_003825515.1 protein YgfX Toxin
FXN82_RS05220 921540..922061 - 522 WP_148361503.1 flavodoxin FldB -
FXN82_RS05225 922175..923071 + 897 WP_126317441.1 site-specific tyrosine recombinase XerD -
FXN82_RS05230 923095..923808 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FXN82_RS05235 923814..925547 + 1734 WP_148361504.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T136936 WP_003825515.1 NZ_CP043009:921031-921438 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T136936 NZ_CP043009:921031-921438 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT136936 WP_003825514.1 NZ_CP043009:920784-921050 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT136936 NZ_CP043009:920784-921050 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References