Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 920784..921438 | Replicon | chromosome |
Accession | NZ_CP043009 | ||
Organism | Citrobacter portucalensis strain WCHCP085039 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | FXN82_RS05215 | Protein ID | WP_003825515.1 |
Coordinates | 921031..921438 (+) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | FXN82_RS05210 | Protein ID | WP_003825514.1 |
Coordinates | 920784..921050 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FXN82_RS05180 | 915940..917373 | - | 1434 | WP_079938634.1 | 6-phospho-beta-glucosidase BglA | - |
FXN82_RS05185 | 917494..918222 | - | 729 | WP_008785744.1 | MurR/RpiR family transcriptional regulator | - |
FXN82_RS05190 | 918275..918586 | + | 312 | WP_148361500.1 | N(4)-acetylcytidine aminohydrolase | - |
FXN82_RS05195 | 918750..919412 | + | 663 | WP_063940912.1 | hemolysin III family protein | - |
FXN82_RS05200 | 919543..920526 | - | 984 | WP_148361501.1 | tRNA-modifying protein YgfZ | - |
FXN82_RS05210 | 920784..921050 | + | 267 | WP_003825514.1 | FAD assembly factor SdhE | Antitoxin |
FXN82_RS05215 | 921031..921438 | + | 408 | WP_003825515.1 | protein YgfX | Toxin |
FXN82_RS05220 | 921540..922061 | - | 522 | WP_148361503.1 | flavodoxin FldB | - |
FXN82_RS05225 | 922175..923071 | + | 897 | WP_126317441.1 | site-specific tyrosine recombinase XerD | - |
FXN82_RS05230 | 923095..923808 | + | 714 | WP_003825520.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
FXN82_RS05235 | 923814..925547 | + | 1734 | WP_148361504.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 15882.76 Da Isoelectric Point: 11.3523
>T136936 WP_003825515.1 NZ_CP043009:921031-921438 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG
Download Length: 408 bp
>T136936 NZ_CP043009:921031-921438 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10615.14 Da Isoelectric Point: 5.1700
>AT136936 WP_003825514.1 NZ_CP043009:920784-921050 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI
Download Length: 267 bp
>AT136936 NZ_CP043009:920784-921050 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|