Detailed information of TA system TA136932

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 65106..65786
• Replicon: chromosome
• Accession: NZ_CP043009
• Organism: Citrobacter portucalensis strain WCHCP085039

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: FXN82_RS00960
• Protein ID: WP_039026306.1
• Coordinates: 65106..65447 (-)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: FXN82_RS00965
• Protein ID: WP_039026307.1
• Coordinates: 65469..65786 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXN82_RS00930	61353..61727	-	375	WP_057066445.1	hypothetical protein	-
FXN82_RS23700	61717..61860	-	144	WP_187392911.1	hypothetical protein	-
FXN82_RS00935	62062..62403	+	342	WP_148361310.1	hypothetical protein	-
FXN82_RS00940	62491..62781	-	291	WP_148361311.1	SymE family type I addiction module toxin	-
FXN82_RS00945	62918..63112	+	195	WP_008786495.1	toxin-antitoxin system HicB family antitoxin	-
FXN82_RS00950	63121..63687	-	567	WP_003827197.1	hypothetical protein	-
FXN82_RS00955	64157..64990	-	834	WP_039026305.1	DUF4942 domain-containing protein	-
FXN82_RS00960	65106..65447	-	342	WP_039026306.1	TA system toxin CbtA family protein	Toxin
FXN82_RS00965	65469..65786	-	318	WP_039026307.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
FXN82_RS00970	65804..66025	-	222	WP_000691995.1	DUF987 domain-containing protein	-
FXN82_RS00975	66034..66510	-	477	WP_039026308.1	RadC family protein	-
FXN82_RS00980	66526..66984	-	459	WP_039026309.1	antirestriction protein	-
FXN82_RS00985	67099..67323	-	225	WP_039026310.1	DUF905 domain-containing protein	-
FXN82_RS00990	67419..68354	-	936	WP_072038556.1	hypothetical protein	-
FXN82_RS00995	68405..68620	-	216	WP_039026311.1	hypothetical protein	-
FXN82_RS01005	68948..69646	-	699	WP_039026312.1	DeoR family transcriptional regulator	-
FXN82_RS01010	69855..70679	-	825	WP_039026313.1	DUF945 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-112)

Antitoxin

• Antitoxin CbeA (5-104)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12825.82 Da
• Isoelectric Point: 9.7153

>T136932 WP_039026306.1 NZ_CP043009:c65447-65106 [Citrobacter portucalensis]
MKTLPATISRAAKPCLSTVAVWQMLLTRLLEQHYGLTLNDTPFSDVTVIQEHINAGITLADAVNFLVEKYELVRIDRRSF
NCQEQSPYIRAVDILRARQATGLLRQSRNNAVR

Nucleotide

• Length: 342 bp

>T136932 NZ_CP043009:c65447-65106 [Citrobacter portucalensis]
ATGAAAACTCTACCTGCTACAATTTCGCGGGCGGCGAAGCCCTGTCTGTCGACCGTTGCAGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAGCAACACTATGGCCTGACGCTGAACGACACACCATTCAGTGATGTAACCGTTATTCAGGAGCATATCA
ACGCCGGTATTACGCTGGCTGATGCCGTTAACTTTCTGGTGGAAAAGTACGAACTGGTTCGTATCGATCGCAGAAGTTTT
AACTGTCAGGAGCAATCACCTTATATTCGGGCGGTAGATATTTTACGGGCAAGACAGGCAACTGGCCTGTTGCGACAAAG
CCGTAACAACGCAGTACGGTGA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11891.45 Da
• Isoelectric Point: 6.9456

>AT136932 WP_039026307.1 NZ_CP043009:c65786-65469 [Citrobacter portucalensis]
MSNTTWGLQRDITPRMGARLVQEGNRLHYLADRASITSKFSDAECQKLDIAFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGYTCEADTLGSCGYVYIAVYPTQR

Nucleotide

• Length: 318 bp

>AT136932 NZ_CP043009:c65786-65469 [Citrobacter portucalensis]
ATGAGCAACACCACATGGGGCCTGCAGCGGGATATTACACCGCGCATGGGGGCACGTCTGGTACAGGAGGGCAACCGGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCAGTAAGTTTAGTGATGCCGAATGCCAGAAGTTGGATATCGCATTTCCGC
ATTTTATCAGTCAGATGGAATCGATGCTGACCACTGGTGAAATGAATCCTCGGCATGCCCATTGCGTCACCCTGTACCAC
AACGGTTATACCTGCGAAGCCGATACTCTTGGCAGTTGCGGCTACGTATACATCGCTGTTTATCCCACTCAACGCTAA