Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 5196834..5197347 Replicon chromosome
Accession NZ_CP043006
Organism Chitinophaga sp. XS-30

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FW415_RS20900 Protein ID WP_148390024.1
Coordinates 5196834..5197091 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FW415_RS20905 Protein ID WP_148388906.1
Coordinates 5197093..5197347 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FW415_RS20880 5191915..5192802 + 888 WP_148388896.1 T9SS type A sorting domain-containing protein -
FW415_RS20885 5193220..5194230 + 1011 WP_148388898.1 helix-turn-helix domain-containing protein -
FW415_RS20890 5194721..5195050 + 330 WP_148388904.1 hypothetical protein -
FW415_RS20895 5195191..5196684 + 1494 WP_210420754.1 sulfatase-like hydrolase/transferase -
FW415_RS20900 5196834..5197091 - 258 WP_148390024.1 Txe/YoeB family addiction module toxin Toxin
FW415_RS20905 5197093..5197347 - 255 WP_148388906.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FW415_RS20915 5197596..5198408 - 813 WP_148388908.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
FW415_RS20920 5198479..5198676 - 198 WP_148388910.1 hypothetical protein -
FW415_RS20925 5198724..5199011 - 288 WP_148388912.1 SelT/SelW/SelH family protein -
FW415_RS20930 5199008..5199700 - 693 WP_210420755.1 ribose-5-phosphate isomerase RpiA -
FW415_RS20935 5199726..5201663 - 1938 WP_210420926.1 heparinase II/III family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10398.95 Da        Isoelectric Point: 9.4651

>T136930 WP_148390024.1 NZ_CP043006:c5197091-5196834 [Chitinophaga sp. XS-30]
MELVWQTNAWDDYLYWQEQDKKILQRINDLIKDTLRSPFKGIGKPEPLKGDLSGFWSRRITDEHRLVYAVKDKRLHIIQC
RFHYH

Download         Length: 258 bp

>T136930 NZ_CP056329:730041-730526 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9761.14 Da        Isoelectric Point: 8.5492

>AT136930 WP_148388906.1 NZ_CP043006:c5197347-5197093 [Chitinophaga sp. XS-30]
MRVVNYTEFRNNLTENLNAVNEDREIVVVSRMQGKNVVVMDLDEYNSIQETLHLTSTKANRKRLEDAIAEMNKGKSVKHK
LIEK

Download         Length: 255 bp

>AT136930 NZ_CP043006:c5197347-5197093 [Chitinophaga sp. XS-30]
ATGAGAGTAGTTAATTATACAGAATTCCGTAATAATCTCACTGAAAACCTGAACGCGGTAAATGAGGATAGAGAAATTGT
AGTCGTTTCCAGAATGCAGGGTAAAAATGTGGTGGTAATGGATTTAGATGAATATAATTCTATCCAGGAAACATTGCATC
TGACCAGCACCAAAGCTAACAGAAAGAGACTGGAAGATGCAATAGCAGAAATGAATAAAGGCAAATCCGTTAAACATAAA
CTTATTGAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References