Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1301900..1302435 Replicon chromosome
Accession NZ_CP043005
Organism Aggregatibacter actinomycetemcomitans strain PN_696

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FXN57_RS06815 Protein ID WP_019518289.1
Coordinates 1301900..1302184 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXN57_RS06820 Protein ID WP_005574425.1
Coordinates 1302181..1302435 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN57_RS06790 (FXN57_06785) 1297273..1299249 + 1977 WP_148325453.1 exodeoxyribonuclease V subunit alpha -
FXN57_RS06795 (FXN57_06790) 1299262..1299858 + 597 WP_148363405.1 class I SAM-dependent methyltransferase -
FXN57_RS06800 (FXN57_06795) 1300102..1300530 + 429 WP_005546126.1 50S ribosomal protein L13 -
FXN57_RS06805 (FXN57_06800) 1300547..1300939 + 393 WP_005542159.1 30S ribosomal protein S9 -
FXN57_RS06810 (FXN57_06805) 1301102..1301887 + 786 WP_148363406.1 tRNA pseudouridine(38-40) synthase TruA -
FXN57_RS06815 (FXN57_06810) 1301900..1302184 - 285 WP_019518289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXN57_RS06820 (FXN57_06815) 1302181..1302435 - 255 WP_005574425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXN57_RS06825 (FXN57_06820) 1302652..1304109 - 1458 WP_148325451.1 DASS family sodium-coupled anion symporter -
FXN57_RS06830 (FXN57_06825) 1304336..1305115 + 780 WP_148325450.1 MmcQ/YjbR family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(18-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11203.22 Da        Isoelectric Point: 10.6072

>T136922 WP_019518289.1 NZ_CP043005:c1302184-1301900 [Aggregatibacter actinomycetemcomitans]
MSYIIEFIPSSEKEFRKLDINLRKQFIEKLKERAENPRVSSAKLHGMKDCYKIKLRNVGYHLVYQVIDERIVVKVISVGK
RDRNFVYTKAKSRL

Download         Length: 285 bp

>T136922 NZ_CP043005:c1302184-1301900 [Aggregatibacter actinomycetemcomitans]
ATGAGTTACATCATTGAGTTTATCCCATCATCTGAAAAAGAATTCCGCAAACTCGATATTAATCTGCGTAAACAATTCAT
TGAGAAATTAAAAGAACGCGCCGAAAATCCCCGAGTGTCATCCGCCAAATTACACGGCATGAAAGATTGCTATAAAATCA
AATTACGCAATGTAGGGTATCATTTGGTGTATCAGGTTATTGATGAACGCATTGTGGTCAAAGTCATCTCCGTAGGAAAA
CGCGATCGAAATTTTGTTTATACCAAAGCAAAAAGCAGGCTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.91 Da        Isoelectric Point: 4.1191

>AT136922 WP_005574425.1 NZ_CP043005:c1302435-1302181 [Aggregatibacter actinomycetemcomitans]
MTSLVLTDVVASITELKTNPMAVLREAGGKPLAILNRNEPAFYCVPPAIYEYLMELVDDAELTKIVEERQHEKSYPVDLE
DLLQ

Download         Length: 255 bp

>AT136922 NZ_CP043005:c1302435-1302181 [Aggregatibacter actinomycetemcomitans]
ATGACAAGCCTTGTTTTAACCGATGTTGTCGCCAGTATCACCGAATTAAAAACTAATCCCATGGCGGTACTTCGTGAAGC
CGGTGGAAAACCGCTGGCAATTTTAAACCGCAATGAACCCGCATTTTATTGCGTCCCACCGGCAATTTATGAATATTTGA
TGGAATTAGTCGATGATGCTGAATTGACAAAAATCGTGGAAGAACGTCAACATGAAAAAAGTTATCCTGTTGATTTAGAG
GATTTACTACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References