Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1562114..1562649 Replicon chromosome
Accession NZ_CP043004
Organism Aggregatibacter actinomycetemcomitans strain HK_973

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FXN59_RS08110 Protein ID WP_148327191.1
Coordinates 1562114..1562398 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXN59_RS08115 Protein ID WP_005574425.1
Coordinates 1562395..1562649 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN59_RS08085 (FXN59_08085) 1557484..1559463 + 1980 WP_148327193.1 exodeoxyribonuclease V subunit alpha -
FXN59_RS08090 (FXN59_08090) 1559476..1560072 + 597 WP_005546127.1 class I SAM-dependent methyltransferase -
FXN59_RS08095 (FXN59_08095) 1560316..1560744 + 429 WP_148327192.1 50S ribosomal protein L13 -
FXN59_RS08100 (FXN59_08100) 1560761..1561153 + 393 WP_005542159.1 30S ribosomal protein S9 -
FXN59_RS08105 (FXN59_08105) 1561316..1562101 + 786 WP_005574423.1 tRNA pseudouridine(38-40) synthase TruA -
FXN59_RS08110 (FXN59_08110) 1562114..1562398 - 285 WP_148327191.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXN59_RS08115 (FXN59_08115) 1562395..1562649 - 255 WP_005574425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXN59_RS08120 (FXN59_08120) 1562866..1564323 - 1458 WP_151294665.1 DASS family sodium-coupled anion symporter -
FXN59_RS08125 (FXN59_08125) 1564550..1565329 + 780 WP_151294667.1 MmcQ/YjbR family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11213.26 Da        Isoelectric Point: 10.6072

>T136916 WP_148327191.1 NZ_CP043004:c1562398-1562114 [Aggregatibacter actinomycetemcomitans]
MSYIIEFIPSSEKEFRKLDINLRKQFIEKLKERAENPRVSSAKLHGMKDCYKIKLRNVGYHLVYQVIDERIVVKVIPVGK
RDRNFVYTKAKSRL

Download         Length: 285 bp

>T136916 NZ_CP043004:c1562398-1562114 [Aggregatibacter actinomycetemcomitans]
ATGAGTTACATCATTGAGTTTATCCCATCATCTGAAAAAGAATTCCGCAAACTCGATATTAATCTGCGTAAACAATTCAT
TGAGAAATTAAAAGAACGCGCCGAAAATCCCCGAGTGTCATCCGCCAAATTACACGGCATGAAAGATTGCTATAAAATCA
AATTACGCAATGTAGGGTATCATTTGGTGTATCAGGTTATTGATGAGCGCATTGTGGTCAAAGTCATCCCCGTAGGAAAA
CGCGATCGAAATTTTGTTTATACCAAAGCAAAAAGCAGGCTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.91 Da        Isoelectric Point: 4.1191

>AT136916 WP_005574425.1 NZ_CP043004:c1562649-1562395 [Aggregatibacter actinomycetemcomitans]
MTSLVLTDVVASITELKTNPMAVLREAGGKPLAILNRNEPAFYCVPPAIYEYLMELVDDAELTKIVEERQHEKSYPVDLE
DLLQ

Download         Length: 255 bp

>AT136916 NZ_CP043004:c1562649-1562395 [Aggregatibacter actinomycetemcomitans]
ATGACAAGCCTTGTTTTAACCGATGTTGTCGCCAGTATCACCGAATTAAAAACTAATCCCATGGCGGTACTTCGTGAAGC
CGGTGGAAAACCGCTGGCAATTTTAAACCGCAATGAACCCGCATTTTATTGCGTCCCACCGGCAATTTATGAATATTTGA
TGGAATTAGTCGATGATGCTGAATTGACAAAAATCGTGGAAGAACGTCAACATGAAAAAAGTTATCCTGTTGATTTAGAG
GATTTACTACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References