Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1771214..1771749 Replicon chromosome
Accession NZ_CP043003
Organism Aggregatibacter actinomycetemcomitans strain HK_907

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FXN58_RS09195 Protein ID WP_019518289.1
Coordinates 1771465..1771749 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXN58_RS09190 Protein ID WP_005574425.1
Coordinates 1771214..1771468 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXN58_RS09180 (FXN58_09175) 1768534..1769313 - 780 WP_148325450.1 MmcQ/YjbR family DNA-binding protein -
FXN58_RS09185 (FXN58_09180) 1769540..1770997 + 1458 WP_148325451.1 DASS family sodium-coupled anion symporter -
FXN58_RS09190 (FXN58_09185) 1771214..1771468 + 255 WP_005574425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXN58_RS09195 (FXN58_09190) 1771465..1771749 + 285 WP_019518289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXN58_RS09200 (FXN58_09195) 1771762..1772547 - 786 WP_005574423.1 tRNA pseudouridine(38-40) synthase TruA -
FXN58_RS09205 (FXN58_09200) 1772710..1773102 - 393 WP_005542159.1 30S ribosomal protein S9 -
FXN58_RS09210 (FXN58_09205) 1773119..1773547 - 429 WP_005546126.1 50S ribosomal protein L13 -
FXN58_RS09215 (FXN58_09210) 1773791..1774387 - 597 WP_148325452.1 class I SAM-dependent methyltransferase -
FXN58_RS09220 (FXN58_09215) 1774400..1776376 - 1977 WP_148325453.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(18-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11203.22 Da        Isoelectric Point: 10.6072

>T136909 WP_019518289.1 NZ_CP043003:1771465-1771749 [Aggregatibacter actinomycetemcomitans]
MSYIIEFIPSSEKEFRKLDINLRKQFIEKLKERAENPRVSSAKLHGMKDCYKIKLRNVGYHLVYQVIDERIVVKVISVGK
RDRNFVYTKAKSRL

Download         Length: 285 bp

>T136909 NZ_CP056307:c4841611-4841270 [Klebsiella pneumoniae]
ATGAAAACCTTACCTGCAACAACTCAGCGGGCGGCTAAGCCGTGCCCGTCTCCCGTGACAGTCTGGCAGATGCTACTTAC
CCGTCTGCTGGAGCAACATTATGGCCTTTCTCTGAATGACACGCCGTTCAGCGATGAAACCGTTATTCAGGAACATATCA
ACGCCGGTATTACGCTGGCTGATGCTGTTAACTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCGCAGAGGGTTT
AACTGTCAGGAACAGTCACCTTATCTACGGGCGGTAGATATTTTACGGGCTCGGCAGGCAACCGGTCTGCTGCAATATCG
TCGTAACACCTTGTCGCTCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.91 Da        Isoelectric Point: 4.1191

>AT136909 WP_005574425.1 NZ_CP043003:1771214-1771468 [Aggregatibacter actinomycetemcomitans]
MTSLVLTDVVASITELKTNPMAVLREAGGKPLAILNRNEPAFYCVPPAIYEYLMELVDDAELTKIVEERQHEKSYPVDLE
DLLQ

Download         Length: 255 bp

>AT136909 NZ_CP043003:1771214-1771468 [Aggregatibacter actinomycetemcomitans]
ATGACAAGCCTTGTTTTAACCGATGTTGTCGCCAGTATCACCGAATTAAAAACTAATCCCATGGCGGTACTTCGTGAAGC
CGGTGGAAAACCGCTGGCAATTTTAAACCGCAATGAACCCGCATTTTATTGCGTCCCACCGGCAATTTATGAATATTTGA
TGGAATTAGTCGATGATGCTGAATTGACAAAAATCGTGGAAGAACGTCAACATGAAAAAAGTTATCCTGTTGATTTAGAG
GATTTACTACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References