Detailed information of TA system TA136892

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 300203..301221
• Replicon: chromosome
• Accession: NZ_CP042997
• Organism: Aquisphaera giovannonii strain OJF2

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: OJF2_RS01075
• Protein ID: WP_148590471.1
• Coordinates: 300658..301221 (+)
• Length: 188 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: OJF2_RS01070
• Protein ID: WP_148590470.1
• Coordinates: 300203..300658 (+)
• Length: 152 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OJF2_RS01050	295242..296393	-	1152	WP_148590462.1	hypothetical protein	-
OJF2_RS01055	296445..297584	-	1140	WP_148590464.1	serine protease	-
OJF2_RS01060	297586..297834	-	249	WP_148590466.1	hypothetical protein	-
OJF2_RS01065	298703..299911	-	1209	WP_148590468.1	IS4 family transposase	-
OJF2_RS01070	300203..300658	+	456	WP_148590470.1	excisionase family DNA-binding protein	Antitoxin
OJF2_RS01075	300658..301221	+	564	WP_148590471.1	PIN domain-containing protein	Toxin
OJF2_RS01080	301957..302205	-	249	WP_148590473.1	hypothetical protein	-
OJF2_RS01085	302228..303103	-	876	WP_148590475.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-114)

Antitoxin

• Helix-turn-helix domain, group 17 (81-129)

Sequences

Toxin

Protein

• Length: 188 a.a.
• Molecular weight: 20595.73 Da
• Isoelectric Point: 6.9712

>T136892 WP_148590471.1 NZ_CP042997:300658-301221 [Aquisphaera giovannonii]
MEPVPTAIVDACVLYSAPVRDLLVRPAQAGVFHARWTADIHDEWIRNVLKNNPRLTRPRLERTRSLMDAAVRDCLVTGYA
DLIDSLTLPDADDRHVLAAAIRAGASLILTFNLKDFPPGDLAPHGVTARHPGALLADLLDAFPDEFLKAIRLQREALKDP
PMSAEDLLARLETAGLARTATRLRQRG

Nucleotide

• Length: 564 bp

>T136892 NZ_CP042997:300658-301221 [Aquisphaera giovannonii]
ATGGAGCCGGTCCCGACCGCCATCGTCGACGCGTGCGTCCTGTATTCCGCCCCCGTCCGCGACCTGCTCGTGCGGCCCGC
CCAGGCGGGGGTCTTCCACGCCCGATGGACCGCCGACATCCACGACGAATGGATCCGCAACGTCCTGAAGAACAATCCCC
GGCTCACCCGGCCCCGGCTGGAGCGCACTCGGTCGCTGATGGATGCCGCCGTCCGCGACTGCCTGGTGACCGGCTACGCG
GACCTGATCGACTCCCTGACGCTCCCGGATGCGGATGATCGGCATGTCCTGGCCGCCGCGATTCGCGCGGGCGCCTCGCT
GATCCTCACATTCAACCTCAAGGATTTCCCGCCCGGGGATCTCGCCCCGCACGGCGTGACGGCCCGCCACCCGGGCGCCC
TCCTGGCCGATCTGCTGGACGCGTTCCCCGACGAGTTCCTCAAGGCGATCCGGCTCCAGAGGGAGGCCCTGAAGGACCCG
CCCATGTCCGCGGAGGACCTCCTTGCCCGATTGGAGACGGCGGGCCTCGCTCGGACCGCGACCCGACTGCGGCAACGCGG
CTGA

Antitoxin

Protein

• Length: 152 a.a.
• Molecular weight: 16288.64 Da
• Isoelectric Point: 5.0179

>AT136892 WP_148590470.1 NZ_CP042997:300203-300658 [Aquisphaera giovannonii]
MTSIRETTPDAADVLMARESLVRIDRMLDGGAVDLRAAAPGGGDAGGEARLPVAAVRALRDILAEMAQGRAVAMVPIQAE
LTTQQAAGLLNVSRPYLIGLLEAGRIPFRLVGQHRRVRLDDLLEYRRRDDEARGRIADELAADAQELGMGY

Nucleotide

• Length: 456 bp

>AT136892 NZ_CP042997:300203-300658 [Aquisphaera giovannonii]
ATGACCTCGATTCGCGAGACGACGCCGGATGCGGCGGACGTGCTGATGGCGCGAGAGTCCCTGGTGCGGATCGACCGGAT
GCTCGACGGCGGCGCGGTCGATCTGCGGGCGGCCGCTCCGGGCGGGGGAGATGCCGGCGGCGAGGCCCGGCTGCCGGTGG
CGGCGGTCCGGGCGCTCAGGGACATCCTGGCGGAGATGGCCCAGGGGCGGGCGGTCGCGATGGTGCCGATCCAGGCCGAG
CTGACGACGCAGCAGGCGGCCGGCCTCCTCAACGTCTCTCGGCCGTACCTCATCGGCCTGCTCGAGGCCGGCCGGATCCC
GTTCCGCCTGGTGGGCCAGCATCGTCGCGTGCGGCTCGACGACTTGCTGGAGTACCGCCGCAGGGATGACGAGGCCCGGG
GCCGCATCGCCGACGAGCTCGCGGCGGACGCCCAGGAGCTGGGCATGGGATACTGA