Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1859514..1859748 | Replicon | chromosome |
| Accession | NZ_CP042980 | ||
| Organism | Shigella flexneri Y strain PE577 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1859515..1859618 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1859514..1859748 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FW259_RS09630 | 1854936..1855403 | - | 468 | Protein_1848 | DNA-binding transcriptional regulator PgrR | - |
| FW259_RS09635 | 1855467..1855777 | + | 311 | Protein_1849 | transposase | - |
| FW259_RS09640 | 1855820..1857029 | - | 1210 | Protein_1850 | IS3 family transposase | - |
| FW259_RS09645 | 1857084..1857932 | + | 849 | Protein_1851 | IS3-like element IS600 family transposase | - |
| FW259_RS09650 | 1858049..1858330 | + | 282 | WP_005127484.1 | excisionase | - |
| FW259_RS09655 | 1858296..1858688 | + | 393 | WP_001189099.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| FW259_RS09660 | 1859007..1859373 | + | 367 | Protein_1854 | tyrosine-type recombinase/integrase | - |
| - | 1859514..1859748 | + | 235 | - | - | Antitoxin |
| - | 1859515..1859618 | - | 104 | - | - | Toxin |
| FW259_RS09665 | 1859776..1860117 | - | 342 | WP_000976476.1 | YebY family protein | - |
| FW259_RS09670 | 1860130..1861002 | - | 873 | Protein_1856 | copper homeostasis membrane protein CopD | - |
| FW259_RS09675 | 1861006..1861380 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| FW259_RS09680 | 1861519..1861749 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| FW259_RS09685 | 1861851..1862507 | + | 657 | Protein_1859 | carbon-nitrogen hydrolase family protein | - |
| FW259_RS09690 | 1862531..1863193 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T136837 NZ_CP042980:c1859618-1859515 [Shigella flexneri Y]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT136837 NZ_CP042980:1859514-1859748 [Shigella flexneri Y]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
