Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3780723..3781347 Replicon chromosome
Accession NZ_CP042968
Organism Bradyrhizobium paxllaeri strain LMTR 21

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LMTR21_RS17950 Protein ID WP_065755152.1
Coordinates 3780723..3781127 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LMTR21_RS17955 Protein ID WP_065755151.1
Coordinates 3781117..3781347 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMTR21_RS17930 3777100..3777432 - 333 WP_065755154.1 DHCW motif cupin fold protein -
LMTR21_RS17935 3777557..3777931 - 375 WP_065755312.1 nuclear transport factor 2 family protein -
LMTR21_RS17940 3778103..3779701 + 1599 WP_065755153.1 glutamine-hydrolyzing GMP synthase -
LMTR21_RS17945 3779746..3780645 + 900 WP_065755311.1 HNH endonuclease -
LMTR21_RS17950 3780723..3781127 - 405 WP_065755152.1 PIN domain-containing protein Toxin
LMTR21_RS17955 3781117..3781347 - 231 WP_065755151.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LMTR21_RS17960 3781485..3782744 + 1260 WP_065755150.1 serine hydrolase -
LMTR21_RS17965 3782888..3783319 + 432 WP_065755149.1 nuclear transport factor 2 family protein -
LMTR21_RS17970 3783587..3784198 + 612 WP_187399366.1 AraC family transcriptional regulator -
LMTR21_RS17975 3785133..3785606 - 474 WP_065755147.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14559.63 Da        Isoelectric Point: 4.8675

>T136743 WP_065755152.1 NZ_CP042968:c3781127-3780723 [Bradyrhizobium paxllaeri]
MPVSFFDTNVLVYLVSGDAAKADRAEAIIAGGGSISVQVLNELANVARRKMQMSWDETHALLNTLRGLLTVHPITVETHD
AGLRIAERYGLSIYDSMIAASALEAGCDTLWSEDMQHGMKLDEGLRIANPFRGV

Download         Length: 405 bp

>T136743 NZ_CP042968:c3781127-3780723 [Bradyrhizobium paxllaeri]
ATGCCCGTTAGTTTTTTCGATACCAACGTCCTCGTCTACCTCGTGTCCGGCGACGCTGCGAAGGCCGATCGGGCGGAAGC
GATCATTGCTGGCGGCGGCTCAATCAGCGTGCAAGTTCTGAACGAACTTGCCAACGTGGCGCGCCGGAAAATGCAGATGT
CCTGGGACGAGACCCATGCATTGCTGAACACGTTGCGTGGCCTGCTGACGGTTCATCCCATCACCGTCGAGACCCACGAC
GCCGGACTCCGTATCGCCGAACGATACGGCCTTTCAATTTATGACTCGATGATCGCCGCCTCGGCCCTGGAGGCCGGTTG
CGACACGCTTTGGTCGGAGGACATGCAGCATGGCATGAAGCTCGACGAGGGCTTACGCATCGCCAATCCGTTTCGTGGTG
TGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8626.95 Da        Isoelectric Point: 10.8838

>AT136743 WP_065755151.1 NZ_CP042968:c3781347-3781117 [Bradyrhizobium paxllaeri]
MQVAKWGNSLAVRLPAVVVEALGLKEGDEIEIHVADRRQFGVARKPGRDELLKRLRAFRGRLPADFKFDRDEANAR

Download         Length: 231 bp

>AT136743 NZ_CP042968:c3781347-3781117 [Bradyrhizobium paxllaeri]
ATGCAGGTCGCAAAATGGGGGAACAGCCTCGCGGTTCGCCTTCCCGCCGTGGTGGTCGAAGCGCTCGGACTCAAGGAAGG
CGATGAGATCGAAATCCACGTCGCCGACAGGCGACAGTTCGGGGTGGCGCGCAAGCCCGGGCGCGACGAGCTGTTGAAAC
GCCTGCGCGCATTCCGCGGCCGCCTCCCTGCCGATTTCAAGTTCGACAGGGACGAGGCGAATGCCCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References