Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2465277..2466034 Replicon chromosome
Accession NZ_CP042968
Organism Bradyrhizobium paxllaeri strain LMTR 21

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag LMTR21_RS11530 Protein ID WP_065756854.1
Coordinates 2465543..2466034 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LMTR21_RS11525 Protein ID WP_065756853.1
Coordinates 2465277..2465546 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMTR21_RS11500 2460869..2461282 + 414 WP_065756847.1 MucR family transcriptional regulator -
LMTR21_RS11505 2461295..2461723 - 429 WP_065756848.1 SufE family protein -
LMTR21_RS11510 2461806..2462234 - 429 WP_065756849.1 DUF5330 domain-containing protein -
LMTR21_RS11515 2462656..2464467 + 1812 WP_065756851.1 PAS domain-containing sensor histidine kinase -
LMTR21_RS11520 2464493..2465203 + 711 WP_065756852.1 peptidoglycan-binding protein -
LMTR21_RS11525 2465277..2465546 + 270 WP_065756853.1 DUF1778 domain-containing protein Antitoxin
LMTR21_RS11530 2465543..2466034 + 492 WP_065756854.1 GNAT family N-acetyltransferase Toxin
LMTR21_RS11535 2466132..2466476 + 345 WP_057863228.1 DUF1491 family protein -
LMTR21_RS11540 2466601..2467578 - 978 WP_065756855.1 DUF2336 domain-containing protein -
LMTR21_RS11550 2468044..2468817 + 774 WP_065756856.1 hypothetical protein -
LMTR21_RS11555 2468844..2470352 - 1509 WP_065756857.1 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-141)

Antitoxin

Vibrio phage ICP1, Orf50

(9-83)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17227.77 Da        Isoelectric Point: 8.2849

>T136741 WP_065756854.1 NZ_CP042968:2465543-2466034 [Bradyrhizobium paxllaeri]
MKLGPPSSIEDGHDVSAFSCGHPALDDWLRRRALANHKSGASRTFVVCEGSRVVAYYALAAGALACAEATGRFRRNMPDP
IPVAILARLAIDNGYQKRGLGRALFRDAALRILGAADAIGIRGLLVHAISEEAASFYRAVGVESSPADPQTLMVTLADLQ
AAL

Download         Length: 492 bp

>T136741 NZ_CP056216:c2570278-2568956 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCACTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10072.61 Da        Isoelectric Point: 10.6886

>AT136741 WP_065756853.1 NZ_CP042968:2465277-2465546 [Bradyrhizobium paxllaeri]
MSATARDTLNMRIKPEDRTLFDWAAKVQGKTRTDFILEAARRAAEEALLDRAVIQVSAKAYADFIARLEAPPSPNKRLKR
TMQGKAPWE

Download         Length: 270 bp

>AT136741 NZ_CP042968:2465277-2465546 [Bradyrhizobium paxllaeri]
ATGTCAGCGACTGCCCGTGACACCCTGAACATGCGCATCAAGCCCGAGGATCGGACTCTGTTCGATTGGGCCGCCAAGGT
TCAAGGCAAGACACGCACCGACTTCATTCTTGAGGCCGCCCGACGCGCTGCCGAAGAGGCGCTGCTCGATCGCGCCGTCA
TCCAGGTAAGTGCCAAGGCTTACGCGGACTTTATTGCACGGCTCGAGGCGCCACCATCGCCGAACAAACGACTCAAGCGC
ACCATGCAGGGTAAGGCTCCCTGGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References