Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 1356916..1358425 Replicon chromosome
Accession NZ_CP042968
Organism Bradyrhizobium paxllaeri strain LMTR 21

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag LMTR21_RS06365 Protein ID WP_065755762.1
Coordinates 1356916..1357785 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag LMTR21_RS06370 Protein ID WP_065755763.1
Coordinates 1357778..1358425 (-) Length 216 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMTR21_RS06345 1351943..1353859 + 1917 WP_065755758.1 hypothetical protein -
LMTR21_RS06350 1353915..1354919 + 1005 WP_065755759.1 hypothetical protein -
LMTR21_RS06355 1355045..1355959 - 915 WP_187399316.1 DUF2726 domain-containing protein -
LMTR21_RS06360 1355972..1356907 - 936 WP_065755761.1 hypothetical protein -
LMTR21_RS06365 1356916..1357785 - 870 WP_065755762.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LMTR21_RS06370 1357778..1358425 - 648 WP_065755763.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LMTR21_RS39930 1358511..1359329 - 819 WP_210250563.1 hypothetical protein -
LMTR21_RS06380 1359372..1360112 - 741 WP_141688572.1 hypothetical protein -
LMTR21_RS06385 1362496..1362750 + 255 WP_084030904.1 hypothetical protein -
LMTR21_RS06390 1362773..1363390 + 618 WP_065755767.1 cell envelope biogenesis protein TolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(14-57)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32739.60 Da        Isoelectric Point: 6.1556

>T136740 WP_065755762.1 NZ_CP042968:c1357785-1356916 [Bradyrhizobium paxllaeri]
MRKPLKNAGASVRARLLNLAKERNEPFDLLLTQYALERLLYRLSISKYKDKFVLKGAMLLRHWLDDPHRPTRDLDLLGFG
ESDPQLTLGLFKEICETQADDGVTFDTGTLEVDTVRDDSGYRGLRLKCYATIDGARVRIVIDIGYGDATEPGLNEIELLP
LLNQPAPRLRAYPPETVIAEKFQAMVHLGLANTRLKDFYDIWVLARTYEFKDDRLARAIEATFARRKTEIPADRPDALTK
AYADDPTKVQQWTVFIQDVAVDPDPLPGVVETLATFLMPHAEKARNLKG

Download         Length: 870 bp

>T136740 NZ_CP042968:c1357785-1356916 [Bradyrhizobium paxllaeri]
ATGCGTAAGCCGCTGAAAAATGCCGGGGCTTCCGTCCGTGCCCGCCTGCTCAATCTTGCGAAAGAGCGCAACGAGCCGTT
CGATCTCCTGCTCACGCAATATGCGCTCGAACGACTGCTCTACCGGCTGAGCATCAGCAAGTACAAGGATAAGTTCGTCC
TCAAAGGTGCCATGCTGCTGCGACACTGGCTCGATGATCCACATCGGCCAACGCGCGACCTCGACCTGCTCGGCTTTGGC
GAGAGCGATCCGCAACTGACCCTAGGTTTATTCAAAGAAATTTGTGAAACCCAAGCCGACGACGGCGTTACGTTCGATAC
CGGTACGCTGGAGGTCGACACGGTTCGCGACGACTCCGGCTATAGGGGCTTACGTCTCAAATGCTATGCTACGATTGACG
GGGCGCGTGTGCGAATTGTCATCGACATCGGCTATGGCGACGCAACCGAGCCGGGGCTAAACGAGATCGAACTCCTGCCG
CTGCTCAACCAGCCAGCGCCGAGGCTGCGGGCCTATCCGCCGGAGACTGTCATTGCCGAAAAATTCCAGGCGATGGTCCA
TCTTGGCCTTGCCAACACGCGTTTGAAGGATTTCTACGATATCTGGGTCCTTGCCCGAACCTACGAGTTCAAGGACGATC
GCCTCGCGCGCGCAATTGAAGCTACCTTCGCGCGACGAAAGACCGAGATTCCAGCGGATCGACCGGACGCCCTCACCAAG
GCGTATGCGGATGATCCGACCAAGGTCCAGCAATGGACGGTCTTTATCCAGGACGTTGCAGTCGATCCCGATCCTCTTCC
TGGTGTCGTCGAGACGCTCGCCACTTTCCTAATGCCCCACGCAGAAAAGGCGCGGAATTTGAAAGGCTAG

Antitoxin


Download         Length: 216 a.a.        Molecular weight: 24131.90 Da        Isoelectric Point: 10.1542

>AT136740 WP_065755763.1 NZ_CP042968:c1358425-1357778 [Bradyrhizobium paxllaeri]
MKKEPERQEDRAISLLQKRGMMRLSEFLEQGITSATISRMEQKGALNQLSRGLYQLPDALLDSNHSLAVAAKLVPNGVIC
YDSALSFHELTDRIPPYVWMAIGPRDWRPKITRPRIQITRFGPKEFDKGVEHHSIEGVSVSIYTPAKTIVDLFKSGHRQK
AFYNAPAGLAHATQAMKDALRLRKATPSEIAKYAVEAGIWEKIVQPRLEALTVNA

Download         Length: 648 bp

>AT136740 NZ_CP056216:c1832190-1832045 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References