Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1139389..1139921 Replicon chromosome
Accession NZ_CP042966
Organism Sulfurospirillum multivorans strain N

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag SMN_RS05795 Protein ID WP_190278605.1
Coordinates 1139389..1139643 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag SMN_RS05800 Protein ID WP_190278606.1
Coordinates 1139640..1139921 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMN_RS05770 1137255..1137611 + 357 WP_025344304.1 hypothetical protein -
SMN_RS05775 1137624..1138238 - 615 WP_025344305.1 hypothetical protein -
SMN_RS05785 1138398..1138847 + 450 WP_025344306.1 hypothetical protein -
SMN_RS05790 1138883..1139245 + 363 WP_025344307.1 hypothetical protein -
SMN_RS05795 1139389..1139643 + 255 WP_190278605.1 BrnT family toxin Toxin
SMN_RS05800 1139640..1139921 + 282 WP_190278606.1 CopG family transcriptional regulator Antitoxin
SMN_RS05805 1139931..1140437 - 507 WP_025344310.1 hypothetical protein -
SMN_RS05810 1140454..1140768 - 315 WP_025344311.1 hypothetical protein -
SMN_RS05815 1140778..1140960 - 183 WP_148295270.1 hypothetical protein -
SMN_RS05825 1141569..1141820 + 252 WP_084613085.1 hypothetical protein -
SMN_RS05830 1141978..1142172 + 195 WP_025344313.1 hypothetical protein -
SMN_RS05835 1142138..1142617 + 480 WP_025344314.1 hypothetical protein -
SMN_RS05840 1142661..1143278 - 618 WP_025344315.1 hypothetical protein -
SMN_RS05845 1143415..1144098 - 684 WP_025344316.1 phospholipase D family protein -
SMN_RS05850 1144126..1144890 - 765 WP_025344317.1 restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(4-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10082.53 Da        Isoelectric Point: 6.8616

>T136736 WP_190278605.1 NZ_CP042966:1139389-1139643 [Sulfurospirillum multivorans]
MFEYDETKSKANKEKHGIDFEEAQALWQNKQHAVFDSVYVNNEWRHLLVGLIGELCYVAIFTMREDHIRIISVRRCRKNE
KEIL

Download         Length: 255 bp

>T136736 NZ_CP056216:325756-326124 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10771.55 Da        Isoelectric Point: 9.6241

>AT136736 WP_190278606.1 NZ_CP042966:1139640-1139921 [Sulfurospirillum multivorans]
MKTISAEEFDRKFDNGEDILPYIDLSSKRTLKEFEKEMLAVKKVNVDLPSWAIASLDQEAKRMGVTRQSIIKMWLIQKLD
DLSLNRKSLKQVG

Download         Length: 282 bp

>AT136736 NZ_CP042966:1139640-1139921 [Sulfurospirillum multivorans]
ATGAAAACAATATCAGCAGAAGAATTTGATAGAAAATTTGATAATGGTGAAGACATCTTACCTTACATTGATCTCTCTTC
AAAAAGAACGCTTAAAGAGTTTGAGAAAGAGATGTTAGCTGTAAAAAAAGTAAATGTGGATCTTCCATCTTGGGCTATTG
CCTCTTTAGATCAAGAAGCAAAACGTATGGGTGTTACGCGTCAATCTATCATTAAAATGTGGCTTATTCAGAAGCTTGAT
GATCTTAGTCTTAACCGTAAGTCTTTAAAACAAGTGGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References