Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 887152..887818 Replicon chromosome
Accession NZ_CP042941
Organism Atlantibacter hermannii strain ATCC 33651

Toxin (Protein)


Gene name cptA Uniprot ID A0A447LT15
Locus tag FV157_RS04315 Protein ID WP_040459615.1
Coordinates 887152..887571 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID H5V069
Locus tag FV157_RS04320 Protein ID WP_002434469.1
Coordinates 887552..887818 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FV157_RS04295 883144..884877 - 1734 WP_148051815.1 single-stranded-DNA-specific exonuclease RecJ -
FV157_RS04300 884881..885600 - 720 WP_002434476.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FV157_RS04305 885626..886525 - 900 WP_002434475.1 site-specific tyrosine recombinase XerD -
FV157_RS04310 886627..887148 + 522 WP_002434473.1 flavodoxin FldB -
FV157_RS04315 887152..887571 - 420 WP_040459615.1 protein YgfX Toxin
FV157_RS04320 887552..887818 - 267 WP_002434469.1 FAD assembly factor SdhE Antitoxin
FV157_RS04325 888077..889063 + 987 WP_043865941.1 tRNA-modifying protein YgfZ -
FV157_RS04330 889221..889880 - 660 WP_002434465.1 hemolysin III family protein -
FV157_RS04335 890010..890321 - 312 WP_148053058.1 N(4)-acetylcytidine aminohydrolase -
FV157_RS04340 890434..891171 + 738 WP_148051816.1 MurR/RpiR family transcriptional regulator -
FV157_RS04345 891298..892731 + 1434 WP_148053059.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16511.44 Da        Isoelectric Point: 10.5604

>T136644 WP_040459615.1 NZ_CP042941:c887571-887152 [Atlantibacter hermannii]
VVLWQSDLRVSWRAQWFSLMLHGIVAAIILLLPWPLSYMPLWLILLSLVVFDCVRSQRRIHSLQGEVKLTIDYRLRWQGI
EWELTAAPWMLQSGMLLRLRHPDTHRSQHLWLAADSMDAGEWRDLRRILMQQPQSGRHP

Download         Length: 420 bp

>T136644 NZ_CP042941:c887571-887152 [Atlantibacter hermannii]
GTGGTCCTGTGGCAATCTGATCTACGCGTCTCATGGCGCGCACAATGGTTTTCGCTCATGCTTCACGGCATTGTTGCGGC
TATTATTTTATTGCTGCCCTGGCCGTTGAGTTACATGCCGCTCTGGCTGATTTTATTATCATTAGTGGTATTTGATTGCG
TGCGCAGCCAACGGCGCATCCATTCACTGCAAGGTGAAGTCAAACTGACAATTGATTATCGGTTGCGCTGGCAAGGTATC
GAGTGGGAACTGACGGCTGCGCCCTGGATGCTGCAAAGCGGCATGTTGCTGCGCCTGCGTCACCCGGATACACATCGCAG
CCAGCATTTATGGCTTGCGGCAGACAGTATGGACGCAGGCGAATGGCGTGATTTACGGCGGATATTAATGCAGCAACCGC
AAAGCGGTCGCCATCCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10549.05 Da        Isoelectric Point: 5.6178

>AT136644 WP_002434469.1 NZ_CP042941:c887818-887552 [Atlantibacter hermannii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKRVFIRLLECDDPDLFNWLMNHGKPADSELQRMVQMIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT136644 NZ_CP042941:c887818-887552 [Atlantibacter hermannii]
ATGGATATTAATAATAAAGCCCGTATCCACTGGGCATGCCGTCGCGGGATGCGTGAGCTGGATATCTCTATCATGCCGTT
CTTTGAACACGAGTATGACACCCTGAGCGACGACGACAAACGCGTGTTTATTCGTTTGCTCGAATGCGACGACCCCGATC
TTTTTAACTGGTTAATGAATCACGGTAAGCCTGCGGACAGTGAATTGCAGCGCATGGTGCAAATGATTCAAACACGGAAC
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A447LT15

Antitoxin

Source ID Structure
AlphaFold DB H5V069

References