Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4858112..4858383 Replicon chromosome
Accession NZ_CP042892
Organism Escherichia coli O10:H32 strain NMBU-W12E19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4858242..4858345 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4858112..4858383 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVP48_RS25775 4854667..4855329 - 663 WP_000944258.1 exodeoxyribonuclease X -
FVP48_RS25780 4855353..4856009 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FVP48_RS25785 4856111..4856341 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FVP48_RS25790 4856480..4856854 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FVP48_RS25795 4856858..4857730 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
FVP48_RS25800 4857743..4858084 + 342 WP_000976472.1 YebY family protein -
- 4858112..4858383 - 272 - - Antitoxin
- 4858242..4858345 + 104 - - Toxin
FVP48_RS25805 4858480..4859136 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
FVP48_RS25810 4859137..4859328 - 192 WP_001338167.1 YebW family protein -
FVP48_RS25815 4859433..4859669 - 237 WP_001338166.1 DUF1480 family protein -
FVP48_RS25820 4859787..4861226 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T136449 NZ_CP042892:4858242-4858345 [Escherichia coli O10:H32]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT136449 NZ_CP042892:c4858383-4858112 [Escherichia coli O10:H32]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References