Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1916661..1916806 Replicon chromosome
Accession NZ_CP042882
Organism Klebsiella pneumoniae strain NMBU-W07E18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1916697..1916799 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1916661..1916806 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVP31_RS09300 1911791..1913851 + 2061 WP_004151449.1 oligopeptidase B -
FVP31_RS09305 1913855..1914514 - 660 WP_032425085.1 exodeoxyribonuclease X -
FVP31_RS09310 1914593..1914823 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FVP31_RS09315 1914936..1915310 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FVP31_RS09320 1915314..1916183 + 870 WP_099761193.1 copper homeostasis membrane protein CopD -
FVP31_RS09325 1916200..1916538 + 339 WP_016529031.1 YebY family protein -
- 1916661..1916806 - 146 - - Antitoxin
- 1916697..1916799 + 103 - - Toxin
FVP31_RS09330 1917175..1917318 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FVP31_RS09335 1917423..1918391 - 969 WP_004151446.1 VirK/YbjX family protein -
FVP31_RS09340 1918548..1919201 + 654 WP_038807473.1 protein-serine/threonine phosphatase -
FVP31_RS09345 1919198..1919389 - 192 WP_002911395.1 YebW family protein -
FVP31_RS09350 1919487..1919726 - 240 WP_002911393.1 YebV family protein -
FVP31_RS09355 1919842..1921275 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T136401 NZ_CP042882:1916697-1916799 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT136401 NZ_CP042882:c1916806-1916661 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References